Title : Surface decorated magnetic particles in combination with isothermal nucleic acid amplification for rapid pathogen detection

Type of Material: Thesis
Title: Surface decorated magnetic particles in combination with isothermal nucleic acid amplification for rapid pathogen detection
Researcher: Tripathi, Sayantan
Guide: Ghosh, Souradyuti
Department: Department of Chemistry
Publisher: Bennett University
Place: Greater Noida
Year: 2022
Language: English
Subject: Chemistry
Chemistry Analytical
Physical Sciences
Chemistry
Physical and Basic Sciences
Dissertation/Thesis Note: PhD; Department of Chemistry, Bennett University, Greater Noida; 2022
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_464148
040__|dIN-AhILN|aBENN_201310
041__|aeng
100__|eResearcher|aTripathi, Sayantan
110__|aDepartment of Chemistry|0U-0890|dGreater Noida|bBennett University|ein
245__|aSurface decorated magnetic particles in combination with isothermal nucleic acid amplification for rapid pathogen detection
260__|aGreater Noida|c2022|bBennett University
502__|bPhD|d2022|cDepartment of Chemistry, Bennett University, Greater Noida
518__|oDate of Award|d2023
518__|oDate of Completion|d2022
520__|aNucleic acid extraction from clinical samples followed by nucleic acid amplification tests (NAATs) is the key step of conventional molecular diagnostics. Recently, isothermal nucleic acid amplification tests (iNAATs) draw the attention of scientists. These techniques have a significant advantage over conventional NAATs as the detection of the amplicons by iNAATs can be pushed forward using a thermal cycler-free manner, therefore enabling field detection. It helps obtain rapid, quantitative results either in the laboratory or, more importantly, in a resource-limited area. Despite these advantages, prior nucleic acid extraction from the clinical sample is necessary for both NAATs and iNAATs, which need high-cost instruments, a centralized lab, and highly trained personnel. Microfluidic devices can overcome the issue of prior nucleic acid extraction but the complex fabrication procedure of the analytical device makes it non-compatible in the resource-constrained settings by the end-users. Immunoassays could al
650__|aChemistry|2UGC
650__|aPhysical and Basic Sciences|2AIU
653__|aChemistry
653__|aChemistry Analytical
653__|aPhysical Sciences
700__|aGhosh, Souradyuti|eGuide
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/515229|yShodhganga
905__|afromsg

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