| Type of Material: | Thesis |
| Title: | Unravelling complexity of picrosides biosynthetic pathway gene paralogues in a medicinal herb picrorhiza kurroa royle ex benth |
| Researcher: | Kharb, Anjali |
| Guide: | Chauhan, Rajinder Singh |
| Department: | Department of Biotechnology |
| Publisher: | Bennett University |
| Place: | Greater Noida |
| Year: | 2022 |
| Language: | English |
| Subject: | Biochemical Research Methods | Biology and Biochemistry | Biotechnology | Life Sciences | Biotechnology | Life Science |
| Dissertation/Thesis Note: | PhD; Department of Biotechnology, Bennett University, Greater Noida; 2022 |
| Fulltext: | Shodhganga |
| 003 | IN-AhILN | |
| 005 | 2026-10-14 12:05:33 | |
| 008 | __ | 261014t2022||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_464147 |
| 040 | __ | |dIN-AhILN|aBENN_201310 |
| 041 | __ | |aeng |
| 100 | __ | |eResearcher|aKharb, Anjali |
| 110 | __ | |aDepartment of Biotechnology|0U-0890|dGreater Noida|bBennett University|ein |
| 245 | __ | |aUnravelling complexity of picrosides biosynthetic pathway gene paralogues in a medicinal herb picrorhiza kurroa royle ex benth |
| 260 | __ | |aGreater Noida|c2022|bBennett University |
| 502 | __ | |bPhD|d2022|cDepartment of Biotechnology, Bennett University, Greater Noida |
| 518 | __ | |oDate of Award|d2023 |
| 518 | __ | |d2022|oDate of Completion |
| 520 | __ | |aPicrorhiza kurroa is a medicinal herb with Picroside-I and Picroside-II as the major chemical constituents implicated in various pharmacological activities. Being endangered status of herb coupled with chances of adulteration of raw material, a need has been felt to develop alternative production platforms for the production of picrosides, however, that would require a thorough understanding of biosynthetic pathways. The challenge with biosynthetic pathways of secondary metabolites in plants has been the occurrence of multiple copies of genes, thereby, complicating the process of identifying a gene paralogue(s) associated with the biosynthesis of a secondary metabolite in a specific tissue/organ. The final steps in picrosides biosynthesis are the esterification of catalpol (iridoid backbone) for the formation of Picroside-I and Picroside-II, which are catalysed by acyltransferase(s). The current study utilized differential NGS transcriptomics, TPM screening and qRT-PCR for the identification of multiple cop |
| 650 | __ | |aBiotechnology|2UGC |
| 650 | __ | |aLife Science|2AIU |
| 653 | __ | |aBiochemical Research Methods |
| 653 | __ | |aBiology and Biochemistry |
| 653 | __ | |aBiotechnology |
| 653 | __ | |aLife Sciences |
| 700 | __ | |aChauhan, Rajinder Singh|eGuide |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/515227|yShodhganga |
| 905 | __ | |afromsg |
User Feedback Comes Under This section.