Title : Synthesis characterization and biological activity of some novel heterocyclic compounds

Type of Material: Thesis
Title: Synthesis characterization and biological activity of some novel heterocyclic compounds
Researcher: Jadeja Jaysinh Indrajitsinh
Guide: Dr. Mahesh M Savant
Department: Chemistry
Publisher: Atmiya University
Place: Rajkot
Year: 2023
Language: English
Subject: Chemistry
Chemistry Organic
Physical Sciences
Chemistry
Physical and Basic Sciences
Dissertation/Thesis Note: PhD; Chemistry, Atmiya University, Rajkot; 2023
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_464045
040__|dIN-AhILN|aATMI_360005
041__|aeng
100__|eResearcher|aJadeja Jaysinh Indrajitsinh
110__|aChemistry|0U-0967|dRajkot|bAtmiya University|ein
245__|aSynthesis characterization and biological activity of some novel heterocyclic compounds
260__|aRajkot|c2023|bAtmiya University
300__|a312|dDVD|cA4
502__|bPhD|d2023|cChemistry, Atmiya University, Rajkot
518__|oDate of Award|d2024
518__|d2019|oDate of Registration
518__|oDate of Completion|d2023
520__|aThis Ph.D. thesis comprises several chapters focused on the synthesis of various derivatives containing ketene dithioacetal, including thiazole, thiazole hydrazide, and thiophene derivatives, as well as the synthesis of Thiazolo[3,2-a]pyrimidine and its further cyclization to form pyrazolo[3,4-d]thiazolo[3,2-a]pyrimidine derivatives. Chapter 1 describes the synthesis and characterization of a diverse range of thiazole derivatives containing ketene dithioacetal. The synthetic methodologies involve multistep reactions, leading to the formation of structurally diverse compounds. A series of novel ethyl (E)-2- cyano-3-((4-methyl-5-(arylcarbamoyl)thiazol-2-yl)amino)-3-(methylthio)acrylate have been synthesized starting from various 2-amino-N-aryl-4-methylthiazole-5-carboxamide. The significant features of this reaction procedure are novel, modest and short time. Synthesized molecules were evaluated in vitro for their and#945;-amylase inhibitory activity and displayed moderate to excellent inhibition with IC50 va
650__|aChemistry|2UGC
650__|aPhysical and Basic Sciences|2AIU
653__|aChemistry
653__|aChemistry Organic
653__|aPhysical Sciences
700__|aDr. Mahesh M Savant|eGuide
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/597510|yShodhganga
905__|afromsg

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