Title : Design formulate and optimize moxonidine transdermal patch by using different hydrophilic and hydrophobic polymer complexes

Type of Material: Thesis
Title: Design formulate and optimize moxonidine transdermal patch by using different hydrophilic and hydrophobic polymer complexes
Researcher: Abhinay Chhetri
Guide: Biplab Kumar Dey
Department: Department of Pharmaceutical Sciences
Publisher: Assam Don Bosco University
Place: Guwahati
Year: 2019
Language: English
Subject: Clinical Pre Clinical and Health
Pharmacology and Pharmacy
Pharmacology and Toxicology
Pharmacy
Medical and Health Sciences
Dissertation/Thesis Note: PhD; Department of Pharmaceutical Sciences, Assam Don Bosco University, Guwahati; 2019
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_463086
040__|dIN-AhILN|aADBU_781017
041__|aeng
100__|eResearcher|aAbhinay Chhetri
110__|aDepartment of Pharmaceutical Sciences|0U-0049|dGuwahati|bAssam Don Bosco University|ein
245__|aDesign formulate and optimize moxonidine transdermal patch by using different hydrophilic and hydrophobic polymer complexes
260__|aGuwahati|c2019|bAssam Don Bosco University
300__|dDVD
502__|d2019|bPhD|cDepartment of Pharmaceutical Sciences, Assam Don Bosco University, Guwahati
518__|d2020|oDate of Award
518__|d2013|oDate of Registration
518__|oDate of Completion|d2019
520__|aThe objective of the present study remained to formulate Anti-Hypertensive drug (Moxonidine) transdermal patch by Die-cast method by means of different proportion of hydrophobic polymer and hydrophilic polymer with and without enhancer. The prepared transdermal patch of Moxonidine containing, 4% Polyvinyl alcohol as the backing membrane, with the rational blend of polymers along with the required magnitude of drugs, were initiated to be elegant, free from any abnormal deformities. The preformulatory aspects, which included FT-IR studies, revealed out the facts that the polymers used were innocuous and no inconvenient disturbances in the vibration of the functional groups of the molecules were witnessed. The used polymers namely Ethyl cellulose, Acrycoat S-100 as Hydrophobic and Sodium alginate, HPMC as hydrophilic polymer along with the drug Moxonidine were safe for further works.
650__|aPharmacy|2UGC
650__|aMedical and Health Sciences|2AIU
653__|aClinical Pre Clinical and Health
653__|aPharmacology and Pharmacy
653__|aPharmacology and Toxicology
700__|aBiplab Kumar Dey|eGuide
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/455983|yShodhganga
905__|afromsg

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