| Type of Material: | Thesis |
| Title: | Immunogenic potential of a thermostable Mesogenic Newcastle disease virus genotype xiii isolate from Assam |
| Researcher: | Deka, Pubaleem |
| Guide: | Mahato, G. |
| Department: | Veterinary Epidemiology and Preventive Medicine |
| Publisher: | Assam Agricultural University, Johrat |
| Place: | Johrat |
| Year: | 2023 |
| Language: | English |
| Subject: | Life Sciences | Biotechnology | Life Science |
| Dissertation/Thesis Note: | PhD; Veterinary Epidemiology and Preventive Medicine, Assam Agricultural University, Johrat, Johrat; 2023 |
| Fulltext: | Shodhganga |
| 003 | IN-AhILN | |
| 005 | 2026-09-11 17:00:52 | |
| 008 | __ | 260911t2023||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_463040 |
| 040 | __ | |dIN-AhILN|aASAM_785013 |
| 041 | __ | |aeng |
| 100 | __ | |eResearcher|aDeka, Pubaleem |
| 110 | __ | |aVeterinary Epidemiology and Preventive Medicine|0U-0048|dJohrat|bAssam Agricultural University, Johrat|ein |
| 245 | __ | |aImmunogenic potential of a thermostable Mesogenic Newcastle disease virus genotype xiii isolate from Assam |
| 260 | __ | |aJohrat|c2023|bAssam Agricultural University, Johrat |
| 300 | __ | |axiv, 140p. |
| 502 | __ | |d2023|bPhD|cVeterinary Epidemiology and Preventive Medicine, Assam Agricultural University, Johrat, Johrat |
| 518 | __ | |d2023|oDate of Award |
| 518 | __ | |oDate of Registration|d2012 |
| 518 | __ | |oDate of Completion|d2023 |
| 520 | __ | |aNewcastle disease (ND) is a devastating viral disease affecting poultry and has a substantial economic impact on production because of the high morbidity and mortality rates. Only biosecurity measures and adequate vaccination can effectively reduce the economic threat posed by ND. To prevent ND outbreaks, many effective live vaccines are still routinely used. But the use of these vaccines, which are phylogenetically divergent and thermolabile, remains a constraint for controlling ND outbreaks. Therefore, addressing the need for a thermostable genotype-matched vaccine, the present study was undertaken to thermoadapt and attenuate a mesogenic (Genotype XIII) NDV isolate in Vero cells and evaluate its immunogenic potential in chickens. In the present study, the thermostability profile of the NDV isolates was assessed by subjecting them to various temperatures at different time intervals. Of the five NDV isolates, AS/KM/18/32 retained the highest thermal stability based on HA (Log2) titer and infectivity (Log |
| 650 | __ | |aBiotechnology|2UGC |
| 650 | __ | |aLife Science|2AIU |
| 653 | __ | |aLife Sciences |
| 700 | __ | |aMahato, G.|eGuide |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/686038|yShodhganga |
| 905 | __ | |afromsg |
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