Title : Design and synthesis of fused and bridged tetrahydropyran tetrahydrofuran systems trough prins type cascade cyclization

Type of Material: Thesis
Title: Design and synthesis of fused and bridged tetrahydropyran tetrahydrofuran systems trough prins type cascade cyclization
Researcher: Someswarao, B
Guide: Jagan Mohan Reddy, B
Department: Department of Chemistry
Publisher: Adikavi Nannaya University
Place: Rajahmundry
Year: 2017
Language: English
Subject: Chemical Science
Chemistry
Physical and Basic Sciences
Dissertation/Thesis Note: PhD; Department of Chemistry, Adikavi Nannaya University, Rajahmundry; 2017
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_462255
040__|dIN-AhILN|aANUR_533105
041__|aeng
100__|eResearcher|aSomeswarao, B
110__|aDepartment of Chemistry|0U-0005|dRajahmundry|bAdikavi Nannaya University|ein
245__|aDesign and synthesis of fused and bridged tetrahydropyran tetrahydrofuran systems trough prins type cascade cyclization
260__|aRajahmundry|c2017|bAdikavi Nannaya University
300__|a155|dDVD
502__|cDepartment of Chemistry, Adikavi Nannaya University, Rajahmundry|d2017|bPhD
518__|oDate of Award|d2018
518__|oDate of Registration|d2012
518__|oDate of Completion|d2017
520__|aIn organic synthesis, development of novel strategies for heterocyclic compounds is an important goal as many of such compounds display valuable properties. Six-membered oxygen, nitrogen and sulfur containing heterocycles are widely recognized as very important scaffolds in many areas of bio-organic and medicinal chemistry. In particular, the tetrahydropyran ring is featured in a variety of biologically active natural products, marine toxins, and pheromones.1Among various tetrahydropyran ring containing Clavosolides(1), Calyxin(2), Phorboxazoles(3), Centrolobine(4), Laulimalide(5), Kendomycin(6), Leucascandrolide(7) and Polycavernoside(8) are the most important in view of their inherent biological activity.(Figure 1).Therefore it is important to design new and efficient strategies towards such particularly attractive target molecules. Several methods have been devised for construction of tetrahydropyran and piperidine rings. These methods mainly include Prins cyclization,2 hetero-Diels-Alder cycloaddition,3
650__|aChemistry|2UGC
650__|aPhysical and Basic Sciences|2AIU
653__|aChemical Science
700__|aJagan Mohan Reddy, B|eGuide
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/313849|yShodhganga
905__|afromsg

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