| Type of Material: | Thesis |
| Title: | Microbial assessment and antibiogram of bile gallstones and gallbladder tissue in cholecystectomized patients |
| Researcher: | Poonam |
| Guide: | Saini R.G |
| Department: | Department of Interdisciplinary Biomedical Research |
| Publisher: | Adesh University |
| Year: | 2024 |
| Language: | English |
| Subject: | Microbiology | Medical Sciences | Medical and Health Sciences |
| Dissertation/Thesis Note: | PhD; Department of Interdisciplinary Biomedical Research, Adesh University; 2024 |
| Fulltext: | Shodhganga |
| 003 | IN-AhILN | |
| 005 | 2026-08-25 11:52:53 | |
| 008 | __ | 260825t2024||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_462246 |
| 040 | __ | |dIN-AhILN|aADES_151101 |
| 041 | __ | |aeng |
| 100 | __ | |eResearcher|aPoonam |
| 110 | __ | |aDepartment of Interdisciplinary Biomedical Research|0U-0736|dBathinda|bAdesh University|ein |
| 245 | __ | |aMicrobial assessment and antibiogram of bile gallstones and gallbladder tissue in cholecystectomized patients |
| 260 | __ | |bAdesh University|c2024 |
| 300 | __ | |cA4|ai - xvii, 1 - 182 |
| 502 | __ | |cDepartment of Interdisciplinary Biomedical Research, Adesh University|d2024|bPhD |
| 518 | __ | |oDate of Award|d2024 |
| 518 | __ | |oDate of Registration|d2017 |
| 518 | __ | |oDate of Completion|d2024 |
| 520 | __ | |aGastrointestinal disorder cholelithiasis is reported to be associated with female reproductive age, parity and imbalance in the intestinal microbiome. The present study has been carried out to assess the microbial species associated with cholelithiasis by culturing bile, gallstones and gallbladder tissue obtained from 210 subjects. Bile proteome was also analyzed by Mass Spectrophotometry (TIMS-TOF- MS) and the metabolites identified were used to determine the non-culturable microbial species in bile. Eight bacterial species namely E. coli, K. pneumonia, P. aeruginosa, A. baumannii, E. cloacae, S. paratyphii, P. mirabilis and S.marcescens were identified by culturing. Studies on the antibiotic sensitivity indicated that combination of third generation cephalosporins (cefoperazone and sulbactam) is effective against these eight species. Mass spectroscopy of bile identified included 79 different proteins representing 26 immunomodulatory proteins, 3 coagulation proteins, 24 transport proteins, 5 structural pro |
| 650 | __ | |aMedical Sciences|2UGC |
| 650 | __ | |aMedical and Health Sciences|2AIU |
| 653 | __ | |aMicrobiology |
| 700 | __ | |aSaini R.G|eGuide |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/570654|yShodhganga |
| 905 | __ | |afromsg |
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