| Type of Material: | Thesis |
| Title: | Study of mutations in rpo b gene in rifampicin resistant mycobacterium tuberculosis isolates from doda region of jammu and kashmir |
| Researcher: | Akhtar Sameera |
| Guide: | Kaur Amandeep |
| Department: | Department of Interdisciplinary Biomedical Research |
| Publisher: | Adesh University |
| Year: | 2023 |
| Language: | English |
| Subject: | Molecular Biology | Biotechnology | Medical and Health Sciences |
| Dissertation/Thesis Note: | PhD; Department of Interdisciplinary Biomedical Research, Adesh University; 2023 |
| Fulltext: | Shodhganga |
| 003 | IN-AhILN | |
| 005 | 2026-08-25 11:41:01 | |
| 008 | __ | 260825t2023||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_462237 |
| 040 | __ | |aADES_151101|dIN-AhILN |
| 041 | __ | |aeng |
| 100 | __ | |eResearcher|aAkhtar Sameera |
| 110 | __ | |aDepartment of Interdisciplinary Biomedical Research|bAdesh University|dBathinda|ein|0U-0736 |
| 245 | __ | |aStudy of mutations in rpo b gene in rifampicin resistant mycobacterium tuberculosis isolates from doda region of jammu and kashmir |
| 260 | __ | |bAdesh University|c2023 |
| 300 | __ | |dCD|cA4, 8.27 X 11.69 inches|ai - xvi, 1 - 142 |
| 502 | __ | |bPhD|cDepartment of Interdisciplinary Biomedical Research, Adesh University|d2023 |
| 518 | __ | |oDate of Award|d2023 |
| 518 | __ | |oDate of Registration|d2018 |
| 518 | __ | |oDate of Completion|d2023 |
| 520 | __ | |aThe current prospective study aimed to investigate mutations in rpo-B gene in Rifampicin resistant Mycobacterium tuberculosis isolates from Doda region of Jammu and Kashmir. It was observed that, out of 3600 samples processed the specificity of Ziehl- Neelsen (ZN) staining was lower as compared to other methods as 233 patients were found positive using CBNAAT and 203 were found positive with ZN Staining. There were 203 (87.12%) positive cases and 30 (12.88%) negative cases. From both ZN staining and CBNAAT, it was confirmed that mostly positive cases in males were in the age group of 21-90 years while for females, it was 21-80 years. In common for both sexes, maximum TB positivity was seen for 51-60 years (64; 27.46%) and 21-30 years (63; 27.3%). After analysing for rifampicin resistance from 233 pulmonary tuberculosis patients, only 8 patients showed positive results where 2 were from the age group of 11-30 years (25%), 4 from 31-50 years (50%) and 2 were above 50 (25%). It was found that 128 (54.9%) males |
| 650 | __ | |aBiotechnology|2UGC |
| 650 | __ | |aMedical and Health Sciences|2AIU |
| 653 | __ | |aMolecular Biology |
| 700 | __ | |aKaur Amandeep|eGuide |
| 856 | __ | |yShodhganga|uhttp://shodhganga.inflibnet.ac.in/handle/10603/474131 |
| 905 | __ | |afromsg |
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