| Type of Material: | Thesis |
| Title: | Identification and evaluation of phytoestrogens for the management of peripheral insulin resistance |
| Researcher: | Pandey, Jyotsna |
| Guide: | Tamrakar, Akhilesh |
| Department: | Biological Sciences (CSIR-CDRI) |
| Year: | 2019 |
| Language: | English |
| Subject: | Life Sciences | Phytoestrogens | Biotechnology | Life Science |
| Dissertation/Thesis Note: | PhD; 2019 |
| Fulltext: | Shodhganga |
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| 035 | __ | |a(IN-AhILN)th_459919 |
| 040 | __ | |dIN-AhILN|aAcSIR) |
| 041 | __ | |aeng |
| 100 | __ | |eResearcher|aPandey, Jyotsna |
| 110 | __ | |aBiological Sciences (CSIR-CDRI)|ein|b |
| 245 | __ | |aIdentification and evaluation of phytoestrogens for the management of peripheral insulin resistance |
| 260 | __ | |c2019|b |
| 502 | __ | |bPhD|d2019 |
| 518 | __ | |d2019|oDate of Award |
| 518 | __ | |d2016|oDate of Registration |
| 518 | __ | |oDate of Completion|d2019 |
| 520 | __ | |aConclusionOur findings showed that phytoestrogens from the medicinal plants (Cupressus sempervirens, Butea monosperma and murraya koenigii ) act in a similar manner to that like estroge n in utilization of glucose in skeletal mucles cells. BA, BSD, K051, K039 and K012 all the phytoestrogenic molecules activate the P- I- 3- kinase cascade either alone or synergistically with insulin in stimulation of glucose utilization along with GLUT4 translocation in skeletal muscle cells. In mice model of insulin resistance BA have shown an improvement in oral glucose tolerance and amelio rates insulin resistance in skeletal muscle, adipose tissue and liver showing potentials for the management of peripheral insulin resistance. These findings altogether suggests that phytoestrogens have potentials for development as antidiabetic agent for t he management of peripheral insulin resistance and associated complications. |
| 650 | __ | |aBiotechnology|2UGC |
| 650 | __ | |aLife Science|2AIU |
| 653 | __ | |aLife Sciences |
| 653 | __ | |aPhytoestrogens |
| 700 | __ | |aTamrakar, Akhilesh|eGuide |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/372113|yShodhganga |
| 905 | __ | |afromsg |
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