| Type of Material: | Thesis |
| Title: | Protective effect of rumex hastatus leaves extract against hepatic and cognitive decline in animal models of liver cirrhosis |
| Researcher: | Verma, Kapil Kumar |
| Guide: | Goyal, Sachin | Gupta, G.D |
| Department: | School of Pharmacy |
| Publisher: | Abhilashi University |
| Place: | Mandi |
| Year: | 2020 |
| Language: | English |
| Subject: | Clinical Pre Clinical and Health | Pharmacology and Pharmacy | Pharmacology and Toxicology | Pharmacy | Medical and Health Sciences |
| Dissertation/Thesis Note: | PhD; 2020 |
| Fulltext: | Shodhganga |
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| 001 | 459823 | |
| 003 | IN-AhILN | |
| 005 | 2026-05-19 18:20:21 | |
| 008 | __ | 260519t2020||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_459823 |
| 040 | __ | |dIN-AhILN|aABHI_175028 |
| 041 | __ | |aeng |
| 100 | __ | |eResearcher|aVerma, Kapil Kumar |
| 110 | __ | |aSchool of Pharmacy|0U-0761|dMandi|bAbhilashi University|ein |
| 245 | __ | |aProtective effect of rumex hastatus leaves extract against hepatic and cognitive decline in animal models of liver cirrhosis |
| 260 | __ | |aMandi|c2020|bAbhilashi University |
| 502 | __ | |bPhD|d2020 |
| 518 | __ | |d2020|oDate of Award |
| 518 | __ | |d2016|oDate of Registration |
| 518 | __ | |d2020|oDate of Completion |
| 520 | __ | |aRumex hastatus is considered an important traditional folk medicine and commonly used in Himachal Pradesh, India for treating many diseases. In this study, the methanol extract of leaves was evaluated for their protective effect against hepatic and cognition decline in animal models liver cirrhosis; ethanol induced hepatotoxicity and thioacetamide induced hepatotoxicity in rats.newlineLeaves of Rumex hastatus were successively extracted using petroleum ether (PERH), chloroform (CERH), ethyl acetate (EAERH), methanol (MERH) and water (AERH). All the successive solvent extracts were subjected to preface phytochemicals screening for the finding of a mixture of phytoconstituents present in the extracts. Total Phenolic content, total flavonoids and in vitro antioxidant activity of all leaves extracts were carried out by using DPPH assay, reducing power assay, metal chelating activity, nitric oxide assay and H2O2 activity. The maximum safe dose of methanol extract of R. hastatus (MERH) was determined by acute ora |
| 650 | __ | |aPharmacy|2UGC |
| 650 | __ | |aMedical and Health Sciences|2AIU |
| 653 | __ | |aClinical Pre Clinical and Health |
| 653 | __ | |aPharmacology and Pharmacy |
| 653 | __ | |aPharmacology and Toxicology |
| 700 | __ | |aGoyal, Sachin|eGuide |
| 700 | __ | |aGupta, G.D |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/385312|yShodhganga |
| 905 | __ | |afromsg |
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