Title : Formulation Development and Evaluation of Resveratrol Loaded Microcarrier System for the Managemnet of Ulcerative Colitis

Type of Material: Thesis
Title: Formulation Development and Evaluation of Resveratrol Loaded Microcarrier System for the Managemnet of Ulcerative Colitis
Researcher: Kumar, Puneet
Guide: Singla,Shivali
Department: School of Pharmacy
Publisher: Abhilashi University
Place: Mandi
Year: 2024
Language: English
Subject: Clinical Medicine
Clinical Pre Clinical and Health
Dentistry Oral Surgery and Medicine
Medical Sciences
Medical and Health Sciences
Dissertation/Thesis Note: PhD; School of Pharmacy, Abhilashi University, Mandi; 2024
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_456785
040__|aABHI_175028|dIN-AhILN
041__|aeng
100__|aKumar, Puneet|eResearcher
110__|aSchool of Pharmacy|bAbhilashi University|dMandi|ein|0U-1136
245__|aFormulation Development and Evaluation of Resveratrol Loaded Microcarrier System for the Managemnet of Ulcerative Colitis
260__|aMandi|bAbhilashi University|c2024
300__|aAll Pages|cfull|dDVD
502__|cSchool of Pharmacy, Abhilashi University, Mandi|d2024|bPhD
518__|d2024|oDate of Award
518__|oDate of Registration|d2019
518__|oDate of Completion|d2024
520__|aThe present work deals with the formulation and optimization of pectin-based colonnewlinespecific microparticles and pellets containing Resveratrol. Pectin based microparticlesnewlineand pellets coated with Cellulose acetate phthalate containing Resveratrol werenewlineformulated with in five different batches (MF1-MF5 and PF1-PF5). Box-Behnken designnewline(BBD) matrix was applied to optimise the core formulations. Systematic optimization ofnewlineuncoated microsphere was done by Box-Behnken design (BBD) employing three criticalnewlinefactors, pectin concentration (A); Stirring speed (B) and Span 80 concentration (C).newlineParticle size (and#956;m), entrapment efficiency (EE %) and recovery (%) were the key CQAs.newlinePectin microparticles and pellets were coated by CAP using the oil-in-oil solventnewlineevaporation method. Characterisation of the formulations were done by determination ofnewlinepercentage yield, micromeritics properties, drug loading and entrapment efficiencynewlinefollowed by particle s
650__|aMedical Sciences|2UGC
650__|2AIU|aMedical and Health Sciences
653__|aClinical Medicine
653__|aClinical Pre Clinical and Health
653__|aDentistry Oral Surgery and Medicine
700__|eGuide|aSingla,Shivali
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/557439|yShodhganga
905__|afromsg

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