Type of Material: | Thesis |
Title: | Formulation Development and Evaluation of Resveratrol Loaded Microcarrier System for the Managemnet of Ulcerative Colitis |
Researcher: | Kumar, Puneet |
Guide: | Singla,Shivali |
Department: | School of Pharmacy |
Publisher: | Abhilashi University |
Place: | Mandi |
Year: | 2024 |
Language: | English |
Subject: | Clinical Medicine | Clinical Pre Clinical and Health | Dentistry Oral Surgery and Medicine | Medical Sciences | Medical and Health Sciences |
Dissertation/Thesis Note: | PhD; School of Pharmacy, Abhilashi University, Mandi; 2024 |
Fulltext: | Shodhganga |
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003 | IN-AhILN | |
005 | 2024-11-05 13:58:10 | |
008 | __ | 241105t2024||||ii#||||g|m||||||||||eng|| |
035 | __ | |a(IN-AhILN)th_456785 |
040 | __ | |aABHI_175028|dIN-AhILN |
041 | __ | |aeng |
100 | __ | |aKumar, Puneet|eResearcher |
110 | __ | |aSchool of Pharmacy|bAbhilashi University|dMandi|ein|0U-1136 |
245 | __ | |aFormulation Development and Evaluation of Resveratrol Loaded Microcarrier System for the Managemnet of Ulcerative Colitis |
260 | __ | |aMandi|bAbhilashi University|c2024 |
300 | __ | |aAll Pages|cfull|dDVD |
502 | __ | |cSchool of Pharmacy, Abhilashi University, Mandi|d2024|bPhD |
518 | __ | |d2024|oDate of Award |
518 | __ | |oDate of Registration|d2019 |
518 | __ | |oDate of Completion|d2024 |
520 | __ | |aThe present work deals with the formulation and optimization of pectin-based colonnewlinespecific microparticles and pellets containing Resveratrol. Pectin based microparticlesnewlineand pellets coated with Cellulose acetate phthalate containing Resveratrol werenewlineformulated with in five different batches (MF1-MF5 and PF1-PF5). Box-Behnken designnewline(BBD) matrix was applied to optimise the core formulations. Systematic optimization ofnewlineuncoated microsphere was done by Box-Behnken design (BBD) employing three criticalnewlinefactors, pectin concentration (A); Stirring speed (B) and Span 80 concentration (C).newlineParticle size (and#956;m), entrapment efficiency (EE %) and recovery (%) were the key CQAs.newlinePectin microparticles and pellets were coated by CAP using the oil-in-oil solventnewlineevaporation method. Characterisation of the formulations were done by determination ofnewlinepercentage yield, micromeritics properties, drug loading and entrapment efficiencynewlinefollowed by particle s |
650 | __ | |aMedical Sciences|2UGC |
650 | __ | |2AIU|aMedical and Health Sciences |
653 | __ | |aClinical Medicine |
653 | __ | |aClinical Pre Clinical and Health |
653 | __ | |aDentistry Oral Surgery and Medicine |
700 | __ | |eGuide|aSingla,Shivali |
856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/557439|yShodhganga |
905 | __ | |afromsg |
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