| Type of Material: | Thesis |
| Title: | Design and Development of Long acting Formulation for the Treatment of Posterior Segment Eye Diseases |
| Researcher: | Garkal, Atul |
| Guide: | Mehta, Tejal |
| Department: | Institute of Pharmacy |
| Publisher: | Nirma University, Ahmedabad |
| Place: | Ahmedabad |
| Year: | 2023 |
| Language: | English |
| Subject: | Age-related macular degeneration | Anti-VEGF | Clinical Pre Clinical and Health | Pharmacology and Pharmacy | Pharmacology and Toxicology | Pharmacy | Medical Sciences | Medical and Health Sciences |
| Dissertation/Thesis Note: | PhD; Institute of Pharmacy, Nirma University, Ahmedabad, Ahmedabad; 2023 |
| Fulltext: | Shodhganga |
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| 001 | 456589 | |
| 003 | IN-AhILN | |
| 005 | 2024-10-11 12:14:56 | |
| 008 | __ | 241011t2023||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_456589 |
| 040 | __ | |dIN-AhILN|aNIRU_382481 |
| 041 | __ | |aeng |
| 100 | __ | |eResearcher|aGarkal, Atul |
| 110 | __ | |aInstitute of Pharmacy|0U-0146|dAhmedabad|bNirma University, Ahmedabad|ein |
| 245 | __ | |aDesign and Development of Long acting Formulation for the Treatment of Posterior Segment Eye Diseases |
| 260 | __ | |aAhmedabad|c2023|bNirma University, Ahmedabad |
| 300 | __ | |dDVD |
| 502 | __ | |d2023|bPhD|cInstitute of Pharmacy, Nirma University, Ahmedabad, Ahmedabad |
| 518 | __ | |d2023|oDate of Award |
| 518 | __ | |d2019|oDate of Registration |
| 520 | __ | |aAge-related macular degeneration (AMD) is a chronic eye ailment characterized by gradual loss of central vision. Currently, intravitreal injections of anti-VEGF agents are used to manage AMD. However, these injections only halt the progression of the disease. Furthermore, the currently available anti-VEGF agents in the market exhibit a short half-life and hence require frequent administration. Sustained delivery of anti-VEGF agents remains a challenge to deliver across anatomic locations. Innovations in nanotechnology, implantable devices, and formulation strategies hold promise for overcoming these challenges and improving the efficacy of anti-VEGF agents. Polymeric implants with high drug loading capacity can provide sustained delivery of anti-VEGF agents without any complications. Thus, in the present study, an attempt has been made to develop a technique for fabricating cylindrical biodegradable implants which can deliver anti-VEGF agents over 12 months. Small molecule i.e. carotenoid based implants was |
| 650 | __ | |aPharmacy|2UGC |
| 650 | __ | |aMedical Sciences|2UGC |
| 650 | __ | |aMedical and Health Sciences|2AIU |
| 653 | __ | |aAge-related macular degeneration |
| 653 | __ | |aAnti-VEGF |
| 653 | __ | |aClinical Pre Clinical and Health |
| 653 | __ | |aPharmacology and Pharmacy |
| 653 | __ | |aPharmacology and Toxicology |
| 700 | __ | |aMehta, Tejal|eGuide |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/536130|yShodhganga |
| 905 | __ | |afromsg |
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