| Type of Material: | Thesis |
| Title: | Preparation and characterization of BCS class II drugs to enhance physicochemical attributes via cocrystallization approach |
| Researcher: | Vyas, Gunjan |
| Guide: | Shah, Jigar |
| Department: | Institute of Pharmacy |
| Publisher: | Nirma University, Ahmedabad |
| Place: | Ahmedabad |
| Year: | 2024 |
| Language: | English |
| Subject: | Clinical Pre Clinical and Health | Cocrystal formation of Ranolazine | Pharmacology and Pharmacy | Pharmacology and Toxicology | Telmisartan | Pharmacy | Medical Sciences | Medical and Health Sciences |
| Dissertation/Thesis Note: | PhD; Institute of Pharmacy, Nirma University, Ahmedabad, Ahmedabad; 2024 |
| Fulltext: | Shodhganga |
| 000 | 00000ntm a2200000ua 4500 | |
| 001 | 456574 | |
| 003 | IN-AhILN | |
| 005 | 2024-10-11 11:30:39 | |
| 008 | __ | 241011t2024||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_456574 |
| 040 | __ | |aNIRU_382481|dIN-AhILN |
| 041 | __ | |aeng |
| 100 | __ | |aVyas, Gunjan|eResearcher |
| 110 | __ | |aInstitute of Pharmacy|bNirma University, Ahmedabad|dAhmedabad|ein|0U-0146 |
| 245 | __ | |aPreparation and characterization of BCS class II drugs to enhance physicochemical attributes via cocrystallization approach |
| 260 | __ | |aAhmedabad|bNirma University, Ahmedabad|c2024 |
| 300 | __ | |dDVD |
| 502 | __ | |cInstitute of Pharmacy, Nirma University, Ahmedabad, Ahmedabad|d2024|bPhD |
| 518 | __ | |d2024|oDate of Award |
| 518 | __ | |oDate of Registration|d2015 |
| 520 | __ | |aCo-crystallization is now known to be one of the established methods for the improvement of physiochemical properties of drugs in pharmaceutical research and development. With the application of crystal engineering, the conversion of drug moiety into co-crystal form is getting convenient. The Motive behind this work is to convert poor water-soluble drugs into co-crystal forms with the help of various co-crystallization techniques. Techniques that were applied are mainly solvent co-crystallization, co-crystallization by slurry formation, wet milling using Dyno mill, and liquid-assisted co-grinding. Ranolazine was used as a model compound to perform Drug:Coformer crystallization, and Telmisartan (TEL) and Hydrochlorothiazide (HCT) two drug substances was screened for Drug:Drug co-crystalization. Samples obtained from various methods were evaluated by various analytical techniques like microscopy, melting point analysis, X-ray Powder Diffraction (XRPD), and dissolution study. Ranolazine (RAN) exhibits pH-depen |
| 650 | __ | |aPharmacy|2UGC |
| 650 | __ | |aMedical Sciences|2UGC |
| 650 | __ | |aMedical and Health Sciences|2AIU |
| 653 | __ | |aClinical Pre Clinical and Health |
| 653 | __ | |aCocrystal formation of Ranolazine |
| 653 | __ | |aPharmacology and Pharmacy |
| 653 | __ | |aPharmacology and Toxicology |
| 653 | __ | |aTelmisartan |
| 700 | __ | |eGuide|aShah, Jigar |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/546129|yShodhganga |
| 905 | __ | |afromsg |
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