| Type of Material: | Thesis |
| Title: | Formulation Development and Evaluation of Lipidic Nanoformulations for Local Therapy of Oral Cavity Cancer |
| Researcher: | Padma, Kartik |
| Guide: | Mehta, Tejal |
| Department: | Institute of Pharmacy |
| Publisher: | Nirma University, Ahmedabad |
| Place: | Ahmedabad |
| Year: | 2024 |
| Language: | English |
| Subject: | Clinical Pre Clinical and Health | Lipidic Nanoformulations | Oral Cavity Cancer | Pharmacology and Pharmacy | Pharmacology and Toxicology | Medical Sciences | Medical and Health Sciences |
| Dissertation/Thesis Note: | PhD; Institute of Pharmacy, Nirma University, Ahmedabad, Ahmedabad; 2024 |
| Fulltext: | Shodhganga |
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| 001 | 456563 | |
| 003 | IN-AhILN | |
| 005 | 2024-10-11 10:37:20 | |
| 008 | __ | 241011t2024||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_456563 |
| 040 | __ | |aNIRU_382481|dIN-AhILN |
| 041 | __ | |aeng |
| 100 | __ | |aPadma, Kartik|eResearcher |
| 110 | __ | |aInstitute of Pharmacy|bNirma University, Ahmedabad|dAhmedabad|ein|0U-0146 |
| 245 | __ | |aFormulation Development and Evaluation of Lipidic Nanoformulations for Local Therapy of Oral Cavity Cancer |
| 260 | __ | |aAhmedabad|bNirma University, Ahmedabad|c2024 |
| 300 | __ | |dDVD |
| 502 | __ | |cInstitute of Pharmacy, Nirma University, Ahmedabad, Ahmedabad|d2024|bPhD |
| 518 | __ | |d2024|oDate of Award |
| 518 | __ | |oDate of Registration|d2018 |
| 520 | __ | |aOral cancer accounts for more than 30% of cancer in India with 90% of them being oral squamous cell carcinomas (OSCC). It affects the squamous cells of lip, mouth and tongue. Existing standard treatment regimen of chemotherapy and radiation therapy have poor therapeutic outcomes including side effects, off-target effects and toxicity. Furthermore, there are chances of local re-occurrence at the site of tumor, post tumor removal and successful completion of chemotherapy. OSCC also shows overexpression of EGFR which is a major factor for tumor growth and progression and hence it is necessary of control and target EGFR. Tumors developed inside the oral cavity have the potential to be treated by application of therapeutics directly at the site of disease which is also called loco-regional therapy. Such a therapy can reduce dose related toxicities as lower dose of drug will be required, and deliver drugs specifically at the site of disease thus reducing toxicities and side effects to healthy tissues. As per our |
| 650 | __ | |aMedical Sciences|2UGC |
| 650 | __ | |aMedical and Health Sciences|2AIU |
| 653 | __ | |aClinical Pre Clinical and Health |
| 653 | __ | |aLipidic Nanoformulations |
| 653 | __ | |aOral Cavity Cancer |
| 653 | __ | |aPharmacology and Pharmacy |
| 653 | __ | |aPharmacology and Toxicology |
| 700 | __ | |eGuide|aMehta, Tejal |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/561599|yShodhganga |
| 905 | __ | |afromsg |
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