Type of Material: | Thesis |
Title: | Superparamagnetic Customizable Drug Delivery Devices from SPIONs Functionalized with Nanocellulose and Chitosan for Targeted Cancer Therapy by Magnetic Hyperthermia and Magneto Responsive Doxorubicin Delivery Design Synthesis and In vitro Biofunctional Performance Evaluation |
Researcher: | Sumitha, N S |
Guide: | Sailaja, G S |
Department: | Department of Polymer Science and Rubber Technology |
Publisher: | Cochin University of Science & Technology, Cochin |
Place: | Cochin |
Year: | 2023 |
Language: | English |
Subject: | Cancer Biology | Cancer Treatment | Engineering | Engineering and Technology | Engineering Biomedical | Magnetic Hyperthermia | Superparamagnetic Iron Oxide Nanoparticles (SPIONs) | Treatment Strategies | Materials Science | Engineering and Technology |
Dissertation/Thesis Note: | PhD; Department of Polymer Science and Rubber Technology, Cochin University of Science & Technology, Cochin, Cochin |
Fulltext: | Shodhganga |
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001 | 456288 | |
003 | IN-AhILN | |
005 | 2024-10-09 10:11:08 | |
008 | __ | 241009t2023||||ii#||||g|m||||||||||eng|| |
035 | __ | |a(IN-AhILN)th_456288 |
040 | __ | |aCUST_682022|dIN-AhILN |
041 | __ | |aeng |
100 | __ | |aSumitha, N S|eResearcher |
110 | __ | |aDepartment of Polymer Science and Rubber Technology|bCochin University of Science & Technology, Cochin|dCochin|ein|0U-0253 |
245 | __ | |aSuperparamagnetic Customizable Drug Delivery Devices from SPIONs Functionalized with Nanocellulose and Chitosan for Targeted Cancer Therapy by Magnetic Hyperthermia and Magneto Responsive Doxorubicin Delivery Design Synthesis and In vitro Biofunctional Performance Evaluation |
260 | __ | |aCochin|bCochin University of Science & Technology, Cochin|c2023 |
300 | __ | |axxvii, 398|dDVD |
502 | __ | |bPhD|cDepartment of Polymer Science and Rubber Technology, Cochin University of Science & Technology, Cochin, Cochin |
518 | __ | |d2024|oDate of Award |
518 | __ | |d2018|oDate of Registration |
520 | __ | |aDespite extensive research advancements in cancer therapy, the medical community continues to grapple with formidable challenges in the treatment and eradication of cancer that accounts for one-sixth of human deaths. Newer non-invasive and patient-friendly cancer treatment modalities are of utmost importance owing to the severe side effects associated with conventional therapeutic approaches, viz. surgery, chemotherapy, and radiotherapy. Stimuli-responsive drug delivery and magnetic hyperthermia are two such treatment methods gaining increased clinical attention. The former works on the principle of internal and external stimuli-driven release of chemotherapeutics while the latter involves artificially elevating the tumour tissue temperature to 41-43 ºC. This study is focused on the design and development of four customizable stimuli-sensitive drug delivery devices capable of eliciting hyperthermia for cancer treatment. Superparamagnetic iron oxide nanoparticles (SPIONs), surface-functionalized with nanoce |
650 | __ | |aMaterials Science|2UGC |
650 | __ | |aEngineering and Technology|2AIU |
653 | __ | |aCancer Biology |
653 | __ | |aCancer Treatment |
653 | __ | |aEngineering |
653 | __ | |aEngineering and Technology |
653 | __ | |aEngineering Biomedical |
653 | __ | |aMagnetic Hyperthermia |
653 | __ | |aSuperparamagnetic Iron Oxide Nanoparticles (SPIONs) |
653 | __ | |aTreatment Strategies |
700 | __ | |eGuide|aSailaja, G S |
856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/556450|yShodhganga |
905 | __ | |afromsg |
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