| Type of Material: | Thesis |
| Title: | Therapeutic Status of Aswagandharishtam in Cellular Model of Diabetic Neuropathy |
| Researcher: | Kotteeswari, J |
| Guide: | Prabhu, K |
| Department: | Faculty of Medical Sciences |
| Publisher: | Bharath University, Chennai |
| Place: | Chennai |
| Year: | 2022 |
| Language: | English |
| Subject: | Clinical Medicine | Clinical Pre Clinical and Health | Medicine General and Internal | Medical Sciences | Medical and Health Sciences |
| Dissertation/Thesis Note: | PhD; Faculty of Medical Sciences, Bharath University, Chennai, Chennai; 2022; D15MS022 |
| Fulltext: | Shodhganga |
| 000 | 00000ntm a2200000ua 4500 | |
| 001 | 455150 | |
| 003 | IN-AhILN | |
| 005 | 2024-09-23 16:00:42 | |
| 008 | __ | 240923t2022||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_455150 |
| 040 | __ | |aBHAU_600073|dIN-AhILN |
| 041 | __ | |aeng |
| 100 | __ | |aKotteeswari, J|eResearcher |
| 110 | __ | |aFaculty of Medical Sciences|bBharath University, Chennai|dChennai|ein|0U-0446 |
| 245 | __ | |aTherapeutic Status of Aswagandharishtam in Cellular Model of Diabetic Neuropathy |
| 260 | __ | |aChennai|bBharath University, Chennai|c2022 |
| 300 | __ | |dDVD |
| 502 | __ | |cFaculty of Medical Sciences, Bharath University, Chennai, Chennai|d2022|oD15MS022|bPhD |
| 518 | __ | |d2022|oDate of Award |
| 520 | __ | |aDiabetic neuropathies have multifactorial pathogenic mechanisms and hyperglycemia plays an important role in the pathogenesis of diabetic neuropathy. Many herbal drugs, siddha drugs, ayurvedic drugs are the most commonly used for managing diabetic complications like neuropathy and scientific validation, efficacy and safety are to be further assessed by well designed research. To know the neuroprotective role of Aswagandharishtam as preventive, ayurvedic and siddha medicines to treat symptoms of diabetic neuropathy in schwann cell model. In the present study, the neuroprotective activity of aswagandharistham was evaluated in Cellular model. The work involves phytochemical analysis, invitro anti-oxidant studies and neuroprotective assays including gene expression analysis. Aswagandharishtam, was found to have significant cytotoxicity against hyperglycemic schwann cells , thereby justifies its neuroprotective potential on par with the standard drug used for diabetic neuropathy, pregabalin. The hormone, insul |
| 650 | __ | |aMedical Sciences|2UGC |
| 650 | __ | |aMedical and Health Sciences|2AIU |
| 653 | __ | |aClinical Medicine |
| 653 | __ | |aClinical Pre Clinical and Health |
| 653 | __ | |aMedicine General and Internal |
| 700 | __ | |aPrabhu, K|eGuide |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/456435|yShodhganga |
| 905 | __ | |afromsg |
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