Type of Material: | Thesis |
Title: | Neuroprotective Efficacy of Withaferin a On Ageing Mediated Dopaminergic Neurodegeneration An Experimental Study |
Researcher: | RAZIYA BANU, M |
Guide: | . |
Department: | Faculty of Medical Sciences |
Publisher: | Bharath University, Chennai |
Place: | Chennai |
Year: | 2020 |
Language: | English |
Subject: | Clinical Medicine | Clinical Neurology | Clinical Pre Clinical and Health | Medical Sciences | Medical and Health Sciences |
Dissertation/Thesis Note: | PhD; Faculty of Medical Sciences, Bharath University, Chennai, Chennai; 2020; D14MS016 |
Fulltext: | Shodhganga |
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035 | __ | |a(IN-AhILN)th_455062 |
040 | __ | |aBHAU_600073|dIN-AhILN |
041 | __ | |aeng |
100 | __ | |aRAZIYA BANU, M|eResearcher |
110 | __ | |aFaculty of Medical Sciences|bBharath University, Chennai|dChennai|ein|0U-0446 |
245 | __ | |aNeuroprotective Efficacy of Withaferin a On Ageing Mediated Dopaminergic Neurodegeneration An Experimental Study |
260 | __ | |aChennai|bBharath University, Chennai|c2020 |
300 | __ | |dDVD |
502 | __ | |bPhD|cFaculty of Medical Sciences, Bharath University, Chennai, Chennai|d2020|oD14MS016 |
520 | __ | |aAgeing is a process characterized by a slow and gradual decline in the physiological functioning of an individual, physical frailty, motor and cognitive impairments. Degenerative ageing process is the critical cause for various non-communicable ailments like stroke, ischemic cardiovascular disorders, cancer, noninsulin-dependent diabetes mellitus, and neurodegenerative disorders. The brain succumbs to degenerative ageing process readily than any other organ, and more specifically substantia nigra pars compacta (SNpc) in the tectum of the midbrain is more vulnerable. Hence, dopamine synthesis in SNpc and thereby its functions are affected in ageing. Substantia nigra projects its neurons to caudate and putamen nuclei (striatum) forming the nigrostriatal dopaminergic system that plays a vital role in voluntary movement control. Interestingly, the SNpc neuronal loss and concurrent dysfunction of the nigrostriatal dopaminergic system is the primary characteristic of Parkinson s disease (PD). The degenerative age |
650 | __ | |aMedical Sciences|2UGC |
650 | __ | |aMedical and Health Sciences|2AIU |
653 | __ | |aClinical Medicine |
653 | __ | |aClinical Neurology |
653 | __ | |aClinical Pre Clinical and Health |
700 | __ | |a.|eGuide |
856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/371401|yShodhganga |
905 | __ | |afromsg |
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