Title : Neuroprotective Efficacy of Withaferin a On Ageing Mediated Dopaminergic Neurodegeneration An Experimental Study

Type of Material: Thesis
Title: Neuroprotective Efficacy of Withaferin a On Ageing Mediated Dopaminergic Neurodegeneration An Experimental Study
Researcher: RAZIYA BANU, M
Guide: .
Department: Faculty of Medical Sciences
Publisher: Bharath University, Chennai
Place: Chennai
Year: 2020
Language: English
Subject: Clinical Medicine
Clinical Neurology
Clinical Pre Clinical and Health
Medical Sciences
Medical and Health Sciences
Dissertation/Thesis Note: PhD; Faculty of Medical Sciences, Bharath University, Chennai, Chennai; 2020; D14MS016
Fulltext: Shodhganga

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040__|aBHAU_600073|dIN-AhILN
041__|aeng
100__|aRAZIYA BANU, M|eResearcher
110__|aFaculty of Medical Sciences|bBharath University, Chennai|dChennai|ein|0U-0446
245__|aNeuroprotective Efficacy of Withaferin a On Ageing Mediated Dopaminergic Neurodegeneration An Experimental Study
260__|aChennai|bBharath University, Chennai|c2020
300__|dDVD
502__|bPhD|cFaculty of Medical Sciences, Bharath University, Chennai, Chennai|d2020|oD14MS016
520__|aAgeing is a process characterized by a slow and gradual decline in the physiological functioning of an individual, physical frailty, motor and cognitive impairments. Degenerative ageing process is the critical cause for various non-communicable ailments like stroke, ischemic cardiovascular disorders, cancer, noninsulin-dependent diabetes mellitus, and neurodegenerative disorders. The brain succumbs to degenerative ageing process readily than any other organ, and more specifically substantia nigra pars compacta (SNpc) in the tectum of the midbrain is more vulnerable. Hence, dopamine synthesis in SNpc and thereby its functions are affected in ageing. Substantia nigra projects its neurons to caudate and putamen nuclei (striatum) forming the nigrostriatal dopaminergic system that plays a vital role in voluntary movement control. Interestingly, the SNpc neuronal loss and concurrent dysfunction of the nigrostriatal dopaminergic system is the primary characteristic of Parkinson s disease (PD). The degenerative age
650__|aMedical Sciences|2UGC
650__|aMedical and Health Sciences|2AIU
653__|aClinical Medicine
653__|aClinical Neurology
653__|aClinical Pre Clinical and Health
700__|a.|eGuide
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/371401|yShodhganga
905__|afromsg

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