| Type of Material: | Thesis |
| Title: | Effects of Bacopa monnieri on hippocampal adult neurogenesis and neural plasticity against aluminium chloride induced dementia in Wistar rats Behavioural histological molecular and biochemical study |
| Researcher: | Senthil Murugan,M |
| Guide: | Rajesh, Bhargavan |
| Department: | Faculty of Medical Sciences |
| Publisher: | Bharath University, Chennai |
| Place: | Chennai |
| Year: | 2021 |
| Language: | English |
| Subject: | Clinical Medicine | Clinical Neurology | Clinical Pre Clinical and Health | Medical Sciences | Medical and Health Sciences |
| Dissertation/Thesis Note: | PhD; Faculty of Medical Sciences, Bharath University, Chennai, Chennai; 2021; D15MS002 |
| Fulltext: | Shodhganga |
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| 001 | 454937 | |
| 003 | IN-AhILN | |
| 005 | 2024-09-20 10:33:21 | |
| 008 | __ | 240920t2021||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_454937 |
| 040 | __ | |aBHAU_600073|dIN-AhILN |
| 041 | __ | |aeng |
| 100 | __ | |aSenthil Murugan,M|eResearcher |
| 110 | __ | |aFaculty of Medical Sciences|bBharath University, Chennai|dChennai|ein|0U-0446 |
| 245 | __ | |aEffects of Bacopa monnieri on hippocampal adult neurogenesis and neural plasticity against aluminium chloride induced dementia in Wistar rats Behavioural histological molecular and biochemical study |
| 260 | __ | |aChennai|bBharath University, Chennai|c2021 |
| 300 | __ | |dDVD |
| 502 | __ | |bPhD|cFaculty of Medical Sciences, Bharath University, Chennai, Chennai|d2021|oD15MS002 |
| 520 | __ | |aAluminium (Al) is a neurotoxin. Chronic exposure to Al leads to neurodegenerative changes. Furthermore, it causes anxiety on oral administration to rodents. Bacopa monnieri (BM) is used in Ayurveda to ameliorate neurodegenerative changes. However, the potentials of BM in regulation of adult neurogenesis and its anxiolytic properties remain unexplored. This study mainly investigated the capacity of BM in adult neurogenesis and anxiolysis. Aims and objectives: We examined the various parameters such as biochemical, histological and behavioural effects of aluminium in hippocampus of Wistar rats. The hippocampus is concerned with declarative, spatial and episodic memory. Furthermore, we investigated the effect of BM on aluminium induced neurodegeneration and anxiety. We also studied the properties of adult neurogenesis, synaptic integration and reduction of tau formation caused by BM in demented rats. Materials and Methods: Aluminium chloride (AlCl3) was administered to Wistar rats orally for four weeks to brin |
| 650 | __ | |aMedical Sciences|2UGC |
| 650 | __ | |aMedical and Health Sciences|2AIU |
| 653 | __ | |aClinical Medicine |
| 653 | __ | |aClinical Neurology |
| 653 | __ | |aClinical Pre Clinical and Health |
| 700 | __ | |aRajesh, Bhargavan|eGuide |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/349966|yShodhganga |
| 905 | __ | |afromsg |
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