Title : Evaluation of analgesic anti inflammatory Anti ulcer and anti bacterial activity of Indazole and its derivatives

Type of Material: Thesis
Title: Evaluation of analgesic anti inflammatory Anti ulcer and anti bacterial activity of Indazole and its derivatives
Researcher: CHEEKAVOLU CHAKRAPANI
Guide: MUNIAPPAN, M
Department: Faculty of Medical Sciences
Publisher: Bharath University, Chennai
Place: Chennai
Year: 2017
Language: English
Subject: Clinical Pre Clinical and Health
Pharmacology and Pharmacy
Pharmacology and Toxicology
Medical Sciences
Medical and Health Sciences
Dissertation/Thesis Note: PhD; Faculty of Medical Sciences, Bharath University, Chennai, Chennai; 2017; D11MS004
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_454813
040__|aBHAU_600073|dIN-AhILN
041__|aeng
100__|aCHEEKAVOLU CHAKRAPANI|eResearcher
110__|aFaculty of Medical Sciences|bBharath University, Chennai|dChennai|ein|0U-0446
245__|aEvaluation of analgesic anti inflammatory Anti ulcer and anti bacterial activity of Indazole and its derivatives
260__|aChennai|bBharath University, Chennai|c2017
300__|dDVD
502__|bPhD|cFaculty of Medical Sciences, Bharath University, Chennai, Chennai|d2017|oD11MS004
520__|aThe earlier studies reveal the various biological activities of the heterocyclic compound of indazole moiety derivatives, including anti-inflammatory, antimicrobial, anti-HIV, anticancer, hypoglycemic, antiprotozoal, antihypertensive, and other activities. From the observed biological activities of the indazole moiety, this is concluded that the medicinal properties of indazole have to be explored in the near future for the treatment of various physiological and pathological conditions. Non-steroidal anti-inflammatory drugs (NSAIDs) are the most widely used medications in the world; 300 million people worldwide are estimated to use NSAIDs. The pharmacological activity of these agents is related to the suppression of prostaglandin biosynthesis from arachidonic acid by inhibiting the activity of the enzyme cyclooxygenases (COX-1 and COX-2). Therefore chronic use of these nonselective agents may elicit appreciable gastrointestinal ulceration and bleeding. The incidence of clinically significant GI side effects
650__|aMedical Sciences|2UGC
650__|aMedical and Health Sciences|2AIU
653__|aClinical Pre Clinical and Health
653__|aPharmacology and Pharmacy
653__|aPharmacology and Toxicology
700__|aMUNIAPPAN, M|eGuide
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/321470|yShodhganga
905__|afromsg

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