Title : Prevalence and Molecular Characterization Of Candida Species Among Patients with Oral Squamous Cell Carcinoma And Oral Potentially Malignant Disorders With Special Reference to Antifungal Resistance And Virulence

Type of Material: Thesis
Title: Prevalence and Molecular Characterization Of Candida Species Among Patients with Oral Squamous Cell Carcinoma And Oral Potentially Malignant Disorders With Special Reference to Antifungal Resistance And Virulence
Researcher: LEENA SANKARI, S
Guide: MAHALAKSHMI, K
Department: Faculty of Dental Sciences
Publisher: Bharath University, Chennai
Place: Chennai
Year: 2021
Language: English
Subject: Clinical Medicine
Clinical Pre Clinical and Health
Dentistry Oral Surgery and Medicine
Medical Sciences
Medical and Health Sciences
Dissertation/Thesis Note: PhD; Faculty of Dental Sciences, Bharath University, Chennai, Chennai; 2021; D13DS507
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_454800
040__|aBHAU_600073|dIN-AhILN
041__|aeng
100__|aLEENA SANKARI, S|eResearcher
110__|aFaculty of Dental Sciences|bBharath University, Chennai|dChennai|ein|0U-0446
245__|aPrevalence and Molecular Characterization Of Candida Species Among Patients with Oral Squamous Cell Carcinoma And Oral Potentially Malignant Disorders With Special Reference to Antifungal Resistance And Virulence
260__|aChennai|bBharath University, Chennai|c2021
300__|dDVD
502__|bPhD|cFaculty of Dental Sciences, Bharath University, Chennai, Chennai|d2021|oD13DS507
520__|aIntroduction: Candida species has been implicated in oral squamous cell carcinoma (OSCC) and Oral potentially malignant disorders (OPMD). In most times, OSCC are preceded by clinically apparent oral potentially malignant disorders. Depending on the host defense mechanisms or local oral microenvironment , Candida can turn from a common oral commensal into an opportunistic pathogen. In recent era, there has been an increased incidence of non albicans Candida species colonising the oral mucosa .Candida plays a significant role in oral carcinogenesis through production of nitrosamines (Nnitrosobenzylmethylamine) and acetaldehyde (ACH) . Antifungal resistance is also on the rise in recent era. The emergence of resistance among common fungal pathogen like Candida affects the patient clinical management and increases the morbidity among OSCC and OPMD patients. Understanding the factors that contribute to resistance is crucial to overcome resistance and devise better therapeutic alternatives. The present study aims
650__|aMedical Sciences|2UGC
650__|aMedical and Health Sciences|2AIU
653__|aClinical Medicine
653__|aClinical Pre Clinical and Health
653__|aDentistry Oral Surgery and Medicine
700__|aMAHALAKSHMI, K|eGuide
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/321459|yShodhganga
905__|afromsg

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