Type of Material: | Thesis |
Title: | Evaluation of Targeted Delivery of Herbals With Silver Nanoparticles In The Treatment of Cancer |
Researcher: | SENTHIL KUMAR, K |
Guide: | Vasuki, R |
Department: | Department of Biomedical Engineering |
Publisher: | Bharath University, Chennai |
Place: | Chennai |
Year: | 2018 |
Language: | English |
Subject: | Engineering | Engineering and Technology | Engineering Biomedical | Biomedical Engineering | Engineering and Technology |
Dissertation/Thesis Note: | PhD; Department of Biomedical Engineering, Bharath University, Chennai, Chennai; 2018; D11BM001 |
Fulltext: | Shodhganga |
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035 | __ | |a(IN-AhILN)th_454796 |
040 | __ | |aBHAU_600073|dIN-AhILN |
041 | __ | |aeng |
100 | __ | |aSENTHIL KUMAR, K|eResearcher |
110 | __ | |aDepartment of Biomedical Engineering|bBharath University, Chennai|dChennai|ein|0U-0446 |
245 | __ | |aEvaluation of Targeted Delivery of Herbals With Silver Nanoparticles In The Treatment of Cancer |
260 | __ | |aChennai|bBharath University, Chennai|c2018 |
300 | __ | |dDVD |
502 | __ | |bPhD|cDepartment of Biomedical Engineering, Bharath University, Chennai, Chennai|d2018|oD11BM001 |
520 | __ | |aSilver nanoparticles in the range of 75 -150 nm in diameter combined with Anticancer activity herbals are the active principle in targeting and treating cancer cells. This Herbal Silver Nano complex was stabilized by coating it with biodegradable and biocompatible polymer - Poly Ethylene Glycol (PEG). This metal-herb-polymer nano complex or PEGylated Green Synthesized Silver Nanoparticle (PGSN) provides specific cancer cell targeting with long systemic circulation leads to effective treatment. Cancer treatment can target various pathways like Epidermal Growth Factor (EGF), Vascular Endothelial Growth Factor (VEGF), Cyclooxygenase -2 enzyme, Apoptosis induction, Protein kinases and angiogenesis. In which angiogenesis, absence of apoptosis and inflammatory process are playing important role in the promotion of cancer. Enhanced Permeability and Retention effect (EPR) of cancer environment played a major role in passive targeting of cancer site with the help of silver nanoparticle combined with anticancer her |
650 | __ | |aBiomedical Engineering|2UGC |
650 | __ | |aEngineering and Technology|2AIU |
653 | __ | |aEngineering |
653 | __ | |aEngineering and Technology |
653 | __ | |aEngineering Biomedical |
700 | __ | |aVasuki, R|eGuide |
856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/319860|yShodhganga |
905 | __ | |afromsg |
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