Title : Phytochemical analysis and anticandidal efficacy of Azadirachta indica and Ficus benghalensis extracts for the management of denture stomatitis

Type of Material: Thesis
Title: Phytochemical analysis and anticandidal efficacy of Azadirachta indica and Ficus benghalensis extracts for the management of denture stomatitis
Researcher: JACOB MATHEW PHILIP
Guide: MAHALAKSHMI. K
Department: Faculty of Dental Sciences
Publisher: Bharath University, Chennai
Place: Chennai
Year: 2020
Language: English
Subject: Life Sciences
Microbiology
Life Sciences
Life Science
Dissertation/Thesis Note: PhD; Faculty of Dental Sciences, Bharath University, Chennai, Chennai; 2020; D16DS001
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_454623
040__|aBHAU_600073|dIN-AhILN
041__|aeng
100__|aJACOB MATHEW PHILIP|eResearcher
110__|aFaculty of Dental Sciences|bBharath University, Chennai|dChennai|ein
245__|aPhytochemical analysis and anticandidal efficacy of Azadirachta indica and Ficus benghalensis extracts for the management of denture stomatitis
260__|aChennai|bBharath University, Chennai|c2020
300__|dDVD
502__|cFaculty of Dental Sciences, Bharath University, Chennai, Chennai|d2020|oD16DS001|bPhD
518__|oDate of Registration|d2016
520__|aIntroduction: Denture stomatitis may sometimes be associated with Candida especially in acrylic denture wearers with poor denture hygiene. With the appearance of drug resistant strains of Candida albicans, a need for an alternative method to prevent denture stomatitis has been recognized. This research project was done using Azadirachta indica leaf and Ficus benghalensis aerial root extracts, to evaluate and compare their anti- fungal effects. Materials and methods: Minimal inhibitory concentration of herbal extracts of A. indica and F. benghalensis were evaluated for an azole resistant and susceptible strain of C. albicans using various solvents. Fungal adhesion assay, antifungal efficacy, fibroblast cytotoxicity assay and flexural strength testing of acrylic resin discs treated previously with ethanolic herbal extracts were carried out. Phytochemical assay, GCMS, and FTIR were performed to detect the secondary metabolites of the plant extracts. Docking of identified molecules with candidal Nmyristoyltrans
650__|aLife Sciences|2UGC
650__|aLife Science|2AIU
653__|aLife Sciences
653__|aMicrobiology
700__|aMAHALAKSHMI. K|eGuide
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/309657|yShodhganga
905__|afromsg

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