Type of Material: | Thesis |
Title: | Phytochemical analysis and anticandidal efficacy of Azadirachta indica and Ficus benghalensis extracts for the management of denture stomatitis |
Researcher: | JACOB MATHEW PHILIP |
Guide: | MAHALAKSHMI. K |
Department: | Faculty of Dental Sciences |
Publisher: | Bharath University, Chennai |
Place: | Chennai |
Year: | 2020 |
Language: | English |
Subject: | Life Sciences | Microbiology | Life Sciences | Life Science |
Dissertation/Thesis Note: | PhD; Faculty of Dental Sciences, Bharath University, Chennai, Chennai; 2020; D16DS001 |
Fulltext: | Shodhganga |
000 | 00000ntm a2200000ua 4500 | |
001 | 454623 | |
003 | IN-AhILN | |
005 | 2024-09-18 10:40:32 | |
008 | __ | 240918t2020||||ii#||||g|m||||||||||eng|| |
035 | __ | |a(IN-AhILN)th_454623 |
040 | __ | |aBHAU_600073|dIN-AhILN |
041 | __ | |aeng |
100 | __ | |aJACOB MATHEW PHILIP|eResearcher |
110 | __ | |aFaculty of Dental Sciences|bBharath University, Chennai|dChennai|ein |
245 | __ | |aPhytochemical analysis and anticandidal efficacy of Azadirachta indica and Ficus benghalensis extracts for the management of denture stomatitis |
260 | __ | |aChennai|bBharath University, Chennai|c2020 |
300 | __ | |dDVD |
502 | __ | |cFaculty of Dental Sciences, Bharath University, Chennai, Chennai|d2020|oD16DS001|bPhD |
518 | __ | |oDate of Registration|d2016 |
520 | __ | |aIntroduction: Denture stomatitis may sometimes be associated with Candida especially in acrylic denture wearers with poor denture hygiene. With the appearance of drug resistant strains of Candida albicans, a need for an alternative method to prevent denture stomatitis has been recognized. This research project was done using Azadirachta indica leaf and Ficus benghalensis aerial root extracts, to evaluate and compare their anti- fungal effects. Materials and methods: Minimal inhibitory concentration of herbal extracts of A. indica and F. benghalensis were evaluated for an azole resistant and susceptible strain of C. albicans using various solvents. Fungal adhesion assay, antifungal efficacy, fibroblast cytotoxicity assay and flexural strength testing of acrylic resin discs treated previously with ethanolic herbal extracts were carried out. Phytochemical assay, GCMS, and FTIR were performed to detect the secondary metabolites of the plant extracts. Docking of identified molecules with candidal Nmyristoyltrans |
650 | __ | |aLife Sciences|2UGC |
650 | __ | |aLife Science|2AIU |
653 | __ | |aLife Sciences |
653 | __ | |aMicrobiology |
700 | __ | |aMAHALAKSHMI. K|eGuide |
856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/309657|yShodhganga |
905 | __ | |afromsg |
User Feedback Comes Under This section.