| Type of Material: | Thesis |
| Title: | Isolation, purification and characterization of antibacterial principle from Drynaria quercifolia |
| Researcher: | Thomas, Toji |
| Guide: | Sadasivan, C | Kurup, G Muraleedhara |
| Department: | School of Bio Sciences |
| Publisher: | Mahatma Gandhi University, Kottayam |
| Place: | Kottayam |
| Year: | 2007/09 |
| Language: | English |
| Subject: | MIC | Drynaria quercifolia | fern | terpenoid | antibacterial principle | Medical Sciences | Medical and Health Sciences |
| Dissertation/Thesis Note: | PhD; 2007/09 |
| Fulltext: | Shodhganga |
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| 001 | 454432 | |
| 003 | IN-AhILN | |
| 005 | 2024-09-11 17:01:31 | |
| 008 | __ | 240911t1970||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_454432 |
| 040 | __ | |aMGND_686560|dIN-AhILN |
| 041 | __ | |aeng |
| 100 | __ | |aThomas, Toji|eResearcher |
| 110 | __ | |aSchool of Bio Sciences|bMahatma Gandhi University, Kottayam|dKottayam|ein |
| 245 | __ | |aIsolation, purification and characterization of antibacterial principle from Drynaria quercifolia |
| 260 | __ | |aKottayam|bMahatma Gandhi University, Kottayam|c2007/09 |
| 300 | __ | |a174p.|c-|dNone |
| 500 | __ | |aBibliography p.136-174 |
| 502 | __ | |d2007/09|bPhD |
| 518 | __ | |dn.d.|oDate of Award |
| 518 | __ | |oDate of Registration|dn.d. |
| 520 | __ | |aThe present study aims to isolate purify and characterize antibacterial principle from Drynaria quercifolia. Investigation started with antibacterial screening of forty-four ferns and phytochemical evaluation of their extracts. Those plants exhibited greater level of antibacterial activity were evaluated further and Drynaria quercifolia was selected for isolating antibacterial principle. The structure of the antibacterial principle was elucidated by UV, IR, MS, 1HNMR, 13CNMR and Elemental analysis. The compound was identified as (1E, 4E)-1,5-bis (4-hydroxy-3,5-dipropyl phenyl) penta-1,4-dien-3- one. The compound displayed meaningful antibacterial activities with MIC value of 31.25 µg/ml against Staphylococcus aureus, and 62.5 µg/ml against Pseudomonas aeruginosa and Escherichia coli. The effectiveness of the compound as antibiotic could not be equated with standard antibiotics except for P. aeruginosa. The result revealed that the compound could be used as an antibiotic like streptomycin against P. aerugi |
| 650 | __ | |aMedical Sciences|2UGC |
| 650 | __ | |aMedical and Health Sciences|2AIU |
| 653 | __ | |aMIC |
| 653 | __ | |aDrynaria quercifolia |
| 653 | __ | |afern |
| 653 | __ | |aterpenoid |
| 653 | __ | |aantibacterial principle |
| 700 | __ | |aSadasivan, C|eGuide |
| 700 | __ | |eGuide|aKurup, G Muraleedhara |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/7093|yShodhganga |
| 905 | __ | |afromsg |
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