Type of Material: | Thesis |
Title: | Molecular mechanism of Gymnema sylvestre and Karela with respect to their anti diabetic and anti obesity properties |
Researcher: | Mahesh Kumar P. |
Guide: | Venkataranganna M V and Manjunath K |
Department: | Faculty of Biotechnology |
Publisher: | Jawaharlal Nehru Technological University, Hyderabad |
Place: | Hyderabad |
Year: | 2017 |
Language: | English |
Subject: | Anti-diabetic | Anti-obesity | Biotechnology and Applied Microbiology | Gymnema sylvestre | Karela | Life Sciences | Momordica cymbalaria | Biotechnology | Engineering and Technology |
Dissertation/Thesis Note: | PhD; Faculty of Biotechnology, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2017 |
Fulltext: | Shodhganga |
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035 | __ | |a(IN-AhILN)th_454405 |
040 | __ | |aJNTU_500028|dIN-AhILN |
041 | __ | |aeng |
100 | __ | |aMahesh Kumar P.|eResearcher |
110 | __ | |aFaculty of Biotechnology|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017 |
245 | __ | |aMolecular mechanism of Gymnema sylvestre and Karela with respect to their anti diabetic and anti obesity properties |
260 | __ | |aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2017 |
300 | __ | |a343p.|dDVD |
502 | __ | |cFaculty of Biotechnology, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2017|bPhD |
518 | __ | |d2017|oDate of Award |
518 | __ | |oDate of Registration|d2008 |
520 | __ | |aThe present study was undertaken to evaluate the influence of the Gymnema slyvestre, Karela and Momordica cymbalaria [wild karela] on anti-diabetic and anti-obesity molecular mechanistic cascade markers like PPARand#947; (Peroxisome Proliferator Activated Receptor gamma) and GLUT-4 (Glucose transporter-4), Adiponectin, Resistin, leptin , EPB-and#945; , Visfatin, pertaining to antilipidymic andnewlineglucose metabolism, transport. Methanolic leaves extract of Gymnema slyvestre, and methanolic fruit extract of Momordica cymbalaria these plant extracts were analysed with different concentrations andnewlinecombinations to screen for potent anti-diabetic as well as anti-obesity properties employing cell based assays.newlinePlant extracts of Gymnema, Karela, Momordica cymbalaria fruit extract ranging from 62.5 to 750 and#956;g/mL were evaluated for glucose uptake activity in vitro using L6 myotubes, Rosiglitazone was used asnewlinea reference standard. |
650 | __ | |aBiotechnology|2UGC |
650 | __ | |aEngineering and Technology|2AIU |
653 | __ | |aAnti-diabetic |
653 | __ | |aAnti-obesity |
653 | __ | |aBiotechnology and Applied Microbiology |
653 | __ | |aGymnema sylvestre |
653 | __ | |aKarela |
653 | __ | |aLife Sciences |
653 | __ | |aMomordica cymbalaria |
700 | __ | |eGuide|aVenkataranganna M V and Manjunath K |
856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/315835|yShodhganga |
905 | __ | |afromsg |
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