Title : Molecular mechanism of Gymnema sylvestre and Karela with respect to their anti diabetic and anti obesity properties

Type of Material: Thesis
Title: Molecular mechanism of Gymnema sylvestre and Karela with respect to their anti diabetic and anti obesity properties
Researcher: Mahesh Kumar P.
Guide: Venkataranganna M V and Manjunath K
Department: Faculty of Biotechnology
Publisher: Jawaharlal Nehru Technological University, Hyderabad
Place: Hyderabad
Year: 2017
Language: English
Subject: Anti-diabetic
Anti-obesity
Biotechnology and Applied Microbiology
Gymnema sylvestre
Karela
Life Sciences
Momordica cymbalaria
Biotechnology
Engineering and Technology
Dissertation/Thesis Note: PhD; Faculty of Biotechnology, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2017
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_454405
040__|aJNTU_500028|dIN-AhILN
041__|aeng
100__|aMahesh Kumar P.|eResearcher
110__|aFaculty of Biotechnology|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017
245__|aMolecular mechanism of Gymnema sylvestre and Karela with respect to their anti diabetic and anti obesity properties
260__|aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2017
300__|a343p.|dDVD
502__|cFaculty of Biotechnology, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2017|bPhD
518__|d2017|oDate of Award
518__|oDate of Registration|d2008
520__|aThe present study was undertaken to evaluate the influence of the Gymnema slyvestre, Karela and Momordica cymbalaria [wild karela] on anti-diabetic and anti-obesity molecular mechanistic cascade markers like PPARand#947; (Peroxisome Proliferator Activated Receptor gamma) and GLUT-4 (Glucose transporter-4), Adiponectin, Resistin, leptin , EPB-and#945; , Visfatin, pertaining to antilipidymic andnewlineglucose metabolism, transport. Methanolic leaves extract of Gymnema slyvestre, and methanolic fruit extract of Momordica cymbalaria these plant extracts were analysed with different concentrations andnewlinecombinations to screen for potent anti-diabetic as well as anti-obesity properties employing cell based assays.newlinePlant extracts of Gymnema, Karela, Momordica cymbalaria fruit extract ranging from 62.5 to 750 and#956;g/mL were evaluated for glucose uptake activity in vitro using L6 myotubes, Rosiglitazone was used asnewlinea reference standard.
650__|aBiotechnology|2UGC
650__|aEngineering and Technology|2AIU
653__|aAnti-diabetic
653__|aAnti-obesity
653__|aBiotechnology and Applied Microbiology
653__|aGymnema sylvestre
653__|aKarela
653__|aLife Sciences
653__|aMomordica cymbalaria
700__|eGuide|aVenkataranganna M V and Manjunath K
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/315835|yShodhganga
905__|afromsg

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