| Type of Material: | Thesis |
| Title: | Design and evaluation of gastroretentive drug delivery systems of anti hypertensives |
| Researcher: | Vishnu Pulavarthy |
| Guide: | Naveen Babu K. |
| Department: | Faculty of Pharmaceutical Sciences |
| Publisher: | Jawaharlal Nehru Technological University, Hyderabad |
| Place: | Hyderabad |
| Year: | 2016 |
| Language: | English |
| Subject: | Immunology | Life Sciences | Pharmacology and Pharmacy | Medical Sciences | Medical and Health Sciences |
| Dissertation/Thesis Note: | PhD; Faculty of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2016 |
| Fulltext: | Shodhganga |
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| 001 | 454317 | |
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| 005 | 2024-08-05 18:07:59 | |
| 008 | __ | 240805t2016||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_454317 |
| 040 | __ | |aJNTU_500028|dIN-AhILN |
| 041 | __ | |aeng |
| 100 | __ | |aVishnu Pulavarthy|eResearcher |
| 110 | __ | |aFaculty of Pharmaceutical Sciences|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017 |
| 245 | __ | |aDesign and evaluation of gastroretentive drug delivery systems of anti hypertensives |
| 260 | __ | |aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2016 |
| 300 | __ | |a240p.|dDVD |
| 502 | __ | |cFaculty of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2016|bPhD |
| 518 | __ | |dJanuary 2016|oDate of Award |
| 518 | __ | |oDate of Registration|d2008-01-01 |
| 520 | __ | |aGastroretentive Drug delivery systems are designed to prolong the gastric residence time after oral administration at specific site and controlling the release of drug, especially for achieving controlled plasma level as well as improving bioavailability. In the present work, an attempt was made to develop Gastroretentive tablets of Eprosartan mesylate, Valsartan and Candesartan cilexetil. These drugs are angiotensin-receptor blockers (ARB) widely prescribed in a variety of cardiac conditions like hypertension, diabetic nephropathy and heart failure. The biological half-life of Eprosartan mesylate is 5-7hours, Valsartan is 3-8 hours and Candesartan cilexetil is 6-9hours. All the above drugs have their maximum absorption in the initial part of gastro intestinal tract, which favours the development of gastro retentive floating dosage form.newline |
| 650 | __ | |aMedical Sciences|2UGC |
| 650 | __ | |2AIU|aMedical and Health Sciences |
| 653 | __ | |aImmunology |
| 653 | __ | |aLife Sciences |
| 653 | __ | |aPharmacology and Pharmacy |
| 700 | __ | |eGuide|aNaveen Babu K. |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/292980|yShodhganga |
| 905 | __ | |afromsg |
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