Type of Material: | Thesis |
Title: | Identification of new molecular inhibitors for novel targets of Mycobacterium tuberculosis an in silico approach |
Researcher: | Kiran Kumar M. |
Guide: | Uma V, Venkata Ramana Reddy Ch. |
Department: | Department of Chemistry |
Publisher: | Jawaharlal Nehru Technological University, Hyderabad |
Place: | Hyderabad |
Year: | 2015 |
Language: | English |
Subject: | Chemistry | Chemistry Medicinal | Molecular inhibitors | Mycobacterium tuberculosis | Physical Sciences |
Dissertation/Thesis Note: | PhD; Department of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2015 |
Fulltext: | Shodhganga |
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035 | __ | |a(IN-AhILN)th_454242 |
040 | __ | |aJNTU_500028|dIN-AhILN |
041 | __ | |aeng |
100 | __ | |aKiran Kumar M.|eResearcher |
110 | __ | |aDepartment of Chemistry|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017 |
245 | __ | |aIdentification of new molecular inhibitors for novel targets of Mycobacterium tuberculosis an in silico approach |
260 | __ | |aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2015 |
300 | __ | |a144p.|dDVD |
502 | __ | |bPhD|cDepartment of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2015 |
518 | __ | |oDate of Award|dSeptember 2015 |
518 | __ | |oDate of Registration|d2011-01-01 |
520 | __ | |aThe aim of the thesis is to design novel newlineleads for Mycobacterium Tuberculosis (Mtb), which can act as potential targets for Tuberculosis (TB) therapy. The challenges in TB therapy are associated with prolonged treatment, drug resistance and inefficacy of drugs against the dormant bacteria. The transcription proteins Sigma F, Sigma L and the efflux protein DrrA are treated as novel drug targets to identify new lead molecules, which can address the lacunae in the present TB therapy.newline |
653 | __ | |aChemistry |
653 | __ | |aChemistry Medicinal |
653 | __ | |aMolecular inhibitors |
653 | __ | |aMycobacterium tuberculosis |
653 | __ | |aPhysical Sciences |
700 | __ | |aUma V, Venkata Ramana Reddy Ch.|eGuide |
856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/291077|yShodhganga |
905 | __ | |afromsg |
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