Title : Identification of new molecular inhibitors for novel targets of Mycobacterium tuberculosis an in silico approach

Type of Material: Thesis
Title: Identification of new molecular inhibitors for novel targets of Mycobacterium tuberculosis an in silico approach
Researcher: Kiran Kumar M.
Guide: Uma V, Venkata Ramana Reddy Ch.
Department: Department of Chemistry
Publisher: Jawaharlal Nehru Technological University, Hyderabad
Place: Hyderabad
Year: 2015
Language: English
Subject: Chemistry
Chemistry Medicinal
Molecular inhibitors
Mycobacterium tuberculosis
Physical Sciences
Dissertation/Thesis Note: PhD; Department of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2015
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_454242
040__|aJNTU_500028|dIN-AhILN
041__|aeng
100__|aKiran Kumar M.|eResearcher
110__|aDepartment of Chemistry|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017
245__|aIdentification of new molecular inhibitors for novel targets of Mycobacterium tuberculosis an in silico approach
260__|aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2015
300__|a144p.|dDVD
502__|bPhD|cDepartment of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2015
518__|oDate of Award|dSeptember 2015
518__|oDate of Registration|d2011-01-01
520__|aThe aim of the thesis is to design novel newlineleads for Mycobacterium Tuberculosis (Mtb), which can act as potential targets for Tuberculosis (TB) therapy. The challenges in TB therapy are associated with prolonged treatment, drug resistance and inefficacy of drugs against the dormant bacteria. The transcription proteins Sigma F, Sigma L and the efflux protein DrrA are treated as novel drug targets to identify new lead molecules, which can address the lacunae in the present TB therapy.newline
653__|aChemistry
653__|aChemistry Medicinal
653__|aMolecular inhibitors
653__|aMycobacterium tuberculosis
653__|aPhysical Sciences
700__|aUma V, Venkata Ramana Reddy Ch.|eGuide
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/291077|yShodhganga
905__|afromsg

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