| Type of Material: | Thesis |
| Title: | Synthesis characterization and pharmacological evaluation of sulfones and sulfonamide derivatives of indole as 5HT6 receptor ligands |
| Researcher: | Thrinath Reddy Bandyala |
| Guide: | Ramakrishna N .V. S. | Mukkanti K. |
| Department: | Department of Chemistry |
| Publisher: | Jawaharlal Nehru Technological University, Hyderabad |
| Place: | Hyderabad |
| Year: | 2016 |
| Language: | English |
| Subject: | Chemistry | Chemistry Medicinal | G-protein coupled receptors (GPCRs) | Indole | Physical Sciences | Serotonin receptors |
| Dissertation/Thesis Note: | PhD; Department of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2016 |
| Fulltext: | Shodhganga |
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| 001 | 454210 | |
| 003 | IN-AhILN | |
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| 008 | __ | 240726t2016||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_454210 |
| 040 | __ | |aJNTU_500028|dIN-AhILN |
| 041 | __ | |aeng |
| 100 | __ | |aThrinath Reddy Bandyala|eResearcher |
| 110 | __ | |aDepartment of Chemistry|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017 |
| 245 | __ | |aSynthesis characterization and pharmacological evaluation of sulfones and sulfonamide derivatives of indole as 5HT6 receptor ligands |
| 260 | __ | |aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2016 |
| 300 | __ | |a262p.|dDVD |
| 502 | __ | |cDepartment of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2016|bPhD |
| 518 | __ | |dFebruary 2016|oDate of Award |
| 518 | __ | |oDate of Registration|d2008-01-01 |
| 520 | __ | |aAccording to a recent survey, almost half of the human diseases and disorders are the ones involving one or more of the G-protein coupled receptors (GPCRs). The GPCRs are the receptors of several endogenous neurotransmitters. Most of the neurotransmitters have been subject to a great deal of research in the past, including acetylcholine, adrenaline, nor-adrenaline, histamine etc; however, due to the lack of enough biochemical information and their physiological roles, some of the serotonin receptors received least attention in the past. However, due to phenomenal growth in the biochemical and genomic sciences, the newer information regarding this receptor family has stimulated a great deal of research in this field. Although the overall distribution and all the existing sub-types of serotonin receptors and their physiological functions are not yet known completely, the drug industry is in a quest to identify more and more new agonist or antagonist ligands for this receptor and its sub-types.Historically, th |
| 653 | __ | |aChemistry |
| 653 | __ | |aChemistry Medicinal |
| 653 | __ | |aG-protein coupled receptors (GPCRs) |
| 653 | __ | |aIndole |
| 653 | __ | |aPhysical Sciences |
| 653 | __ | |aSerotonin receptors |
| 700 | __ | |aRamakrishna N .V. S.|eGuide |
| 700 | __ | |eCo-Guide|aMukkanti K. |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/290347|yShodhganga |
| 905 | __ | |afromsg |
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