Type of Material: | Thesis |
Title: | Design and evaluation of modified drug release multiparticulate drug delivery systems |
Researcher: | Pallavi M Chaudhari |
Guide: | Pravin D Chaudhari |
Department: | Faculty of Pharmaceutical Sciences |
Publisher: | Jawaharlal Nehru Technological University, Hyderabad |
Place: | Hyderabad |
Year: | 2015 |
Language: | English |
Subject: | Clinical Pre Clinical and Health | Drug delivery systems | Pharmacology and Pharmacy | Pharmacology and Toxicology | Medical Sciences | Medical and Health Sciences |
Dissertation/Thesis Note: | PhD; Faculty of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2015 |
Fulltext: | Shodhganga |
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035 | __ | |a(IN-AhILN)th_454204 |
040 | __ | |aJNTU_500028|dIN-AhILN |
041 | __ | |aeng |
100 | __ | |aPallavi M Chaudhari|eResearcher |
110 | __ | |aFaculty of Pharmaceutical Sciences|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017 |
245 | __ | |aDesign and evaluation of modified drug release multiparticulate drug delivery systems |
260 | __ | |aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2015 |
300 | __ | |a175p.|dDVD |
502 | __ | |cFaculty of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2015|bPhD |
518 | __ | |dAugust 2015|oDate of Award |
518 | __ | |oDate of Registration|d2009-01-01 |
520 | __ | |aAs oral route has been used widely for most of the drugs, as it potentiates easy administration, patient compliance. During few decades modified drug delivery system in form of multiparticulates has gain wide importance due to its advantages over conventional dosage forms. So, the plan of current study was to devise modified multiparticulate oral drug delivery systems of Salbutamol sulphate and Gliclazide by use of different techniques with diverse approaches. The Salbutamol sulphate pellets were prepared by solution layering technique and extrusion spheronization techniques, while Gliclazide pellets were prepared only by extrusion spheronization technique. Then the prepared pellets were filled into capsules, as final dosage form. The resulting pellets were evaluated for different in vitro and in-vivo evaluation parameters like drug content, pellet size, drug release, and morphological studies. From the studies it revealed that Eudragit polymers like Eudragit RSPO, Eudragit NE 30D as well as pectin can be u |
650 | __ | |aMedical Sciences|2UGC |
650 | __ | |aMedical and Health Sciences|2AIU |
653 | __ | |aClinical Pre Clinical and Health |
653 | __ | |aDrug delivery systems |
653 | __ | |aPharmacology and Pharmacy |
653 | __ | |aPharmacology and Toxicology |
700 | __ | |eGuide|aPravin D Chaudhari |
856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/289440|yShodhganga |
905 | __ | |afromsg |
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