| Type of Material: | Thesis |
| Title: | Efficacy and safety administration of lacosamide in the treatment of refractory partial epilepsy in pediatric patients |
| Researcher: | Ismail Pasha |
| Guide: | Suresh, D. K. |
| Department: | Faculty of Pharmaceutical Sciences |
| Publisher: | Jawaharlal Nehru Technological University, Hyderabad |
| Place: | Hyderabad |
| Year: | 2015 |
| Language: | English |
| Subject: | Clinical Pre Clinical and Health | Pharmacology and Toxicology | Pharmacology and Pharmacy | Medical Sciences | Medical and Health Sciences |
| Dissertation/Thesis Note: | PhD; Faculty of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2015 |
| Fulltext: | Shodhganga |
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| 003 | IN-AhILN | |
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| 008 | __ | 240724t2015||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_454166 |
| 040 | __ | |aJNTU_500028|dIN-AhILN |
| 041 | __ | |aeng |
| 100 | __ | |aIsmail Pasha|eResearcher |
| 110 | __ | |aFaculty of Pharmaceutical Sciences|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017 |
| 245 | __ | |aEfficacy and safety administration of lacosamide in the treatment of refractory partial epilepsy in pediatric patients |
| 260 | __ | |aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2015 |
| 300 | __ | |dDVD |
| 502 | __ | |cFaculty of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2015|bPhD |
| 518 | __ | |dOctober 2015|oDate of Award |
| 518 | __ | |oDate of Registration|d2008-01-01 |
| 520 | __ | |aA single centre, prospective study was performed to investigate the efficacy and safety of lacosamide as add on therapy in pediatric patients with refractory partial epilepsy.The study was done at Dr. Prabhakar Kore, tertiary care hospital over a period of 30 months duration from Nov 2011 to May 2014. Seventy-ninenewlinepatients with refractory partial epilepsy (age 5 - 15 years), who had notnewlineresponded to more than 2 antiepileptic medications and in whom lacosamidenewlinewas used as add on drug were enrolled. Lacosamide tablets were administerednewlineorally, for one week at a dose of 25 mg twice a day followed by 50 mg twicenewlinedaily for the remaining period. Efficacy, safety and tolerability was assessednewlineduring titration (one month), treatment phase (three months), and subsequentnewlinetwo follow up visits of one month each. Liver function tests (SGOT and SGPT)newlineand EEG were done before enrollment and at the end of treatment period. Patient s care takers or principal investigator obser |
| 650 | __ | |aMedical Sciences|2UGC |
| 650 | __ | |aMedical and Health Sciences|2AIU |
| 653 | __ | |aClinical Pre Clinical and Health |
| 653 | __ | |aPharmacology and Toxicology |
| 653 | __ | |aPharmacology and Pharmacy |
| 700 | __ | |aSuresh, D. K.|eGuide |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/286980|yShodhganga |
| 905 | __ | |afromsg |
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