Type of Material: | Thesis |
Title: | Synthesis and In Vitro Pharmacological Evaluation of Indoles and Alkynyl substituted Thieno Pyrimidines, Indazoles and Pyrazoles |
Researcher: | Gorja, Dhilli Rao |
Guide: | Pal, Manojit | Mukkanti, K. |
Department: | Department of Chemistry |
Publisher: | Jawaharlal Nehru Technological University, Hyderabad |
Place: | Hyderabad |
Year: | 2013 |
Language: | English |
Subject: | Evaluation | Indoles | Pharmacological | Pyrazoles | Synthesis |
Dissertation/Thesis Note: | PhD; Department of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2013 |
Fulltext: | Shodhganga |
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035 | __ | |a(IN-AhILN)th_453938 |
040 | __ | |aJNTU_500028|dIN-AhILN |
041 | __ | |aeng |
100 | __ | |aGorja, Dhilli Rao|eResearcher |
110 | __ | |aDepartment of Chemistry|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017 |
245 | __ | |aSynthesis and In Vitro Pharmacological Evaluation of Indoles and Alkynyl substituted Thieno Pyrimidines, Indazoles and Pyrazoles |
260 | __ | |aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2013 |
300 | __ | |a230 p.|dNone|c- |
500 | __ | |aAppendix and references included in the chapter |
502 | __ | |cDepartment of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2013|bPhD |
520 | __ | |aInvestigations embodied in this thesis entitled Synthesis and In vitro newlinePharmacological Evaluation of Indoles and Alkynyl Substituted Thieno pyrimidines, Indazoles and Pyrazoles have been presented in five chapters as follow: newlineChapter 1: Pd/C mediated alkynylation of N-heterocycles This chapter started with the importance of Sonogashira reactions in C C newlinebond-formation and its wide applications in synthetic and organometallic chemistry. This chapter also deals with the importance, use and versatility of Pd/C catalyst and its advantages over other Pd-catalysts. Pd/C is a cheap and air stable catalyst which can be easily recovered from the reaction newlinemixture and is recyclable. The plausible mechanism associated with the Pd/C mediated coupling reactions is also discussed. The later part of this chapter is based on the various reaction approaches utilizing Pd/C catalyst for the synthesis of alkynylated N-heterocycles. |
653 | __ | |aEvaluation |
653 | __ | |aIndoles |
653 | __ | |aPharmacological |
653 | __ | |aPyrazoles |
653 | __ | |aSynthesis |
700 | __ | |aPal, Manojit|eGuide |
700 | __ | |aMukkanti, K.|eCo-Guide |
856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/19377|yShodhganga |
905 | __ | |afromsg |
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