Title : Synthesis and In Vitro Pharmacological Evaluation of Indoles and Alkynyl substituted Thieno Pyrimidines, Indazoles and Pyrazoles

Type of Material: Thesis
Title: Synthesis and In Vitro Pharmacological Evaluation of Indoles and Alkynyl substituted Thieno Pyrimidines, Indazoles and Pyrazoles
Researcher: Gorja, Dhilli Rao
Guide: Pal, Manojit
Mukkanti, K.
Department: Department of Chemistry
Publisher: Jawaharlal Nehru Technological University, Hyderabad
Place: Hyderabad
Year: 2013
Language: English
Subject: Evaluation
Indoles
Pharmacological
Pyrazoles
Synthesis
Dissertation/Thesis Note: PhD; Department of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2013
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_453938
040__|aJNTU_500028|dIN-AhILN
041__|aeng
100__|aGorja, Dhilli Rao|eResearcher
110__|aDepartment of Chemistry|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017
245__|aSynthesis and In Vitro Pharmacological Evaluation of Indoles and Alkynyl substituted Thieno Pyrimidines, Indazoles and Pyrazoles
260__|aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2013
300__|a230 p.|dNone|c-
500__|aAppendix and references included in the chapter
502__|cDepartment of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2013|bPhD
520__|aInvestigations embodied in this thesis entitled Synthesis and In vitro newlinePharmacological Evaluation of Indoles and Alkynyl Substituted Thieno pyrimidines, Indazoles and Pyrazoles have been presented in five chapters as follow: newlineChapter 1: Pd/C mediated alkynylation of N-heterocycles This chapter started with the importance of Sonogashira reactions in C C newlinebond-formation and its wide applications in synthetic and organometallic chemistry. This chapter also deals with the importance, use and versatility of Pd/C catalyst and its advantages over other Pd-catalysts. Pd/C is a cheap and air stable catalyst which can be easily recovered from the reaction newlinemixture and is recyclable. The plausible mechanism associated with the Pd/C mediated coupling reactions is also discussed. The later part of this chapter is based on the various reaction approaches utilizing Pd/C catalyst for the synthesis of alkynylated N-heterocycles.
653__|aEvaluation
653__|aIndoles
653__|aPharmacological
653__|aPyrazoles
653__|aSynthesis
700__|aPal, Manojit|eGuide
700__|aMukkanti, K.|eCo-Guide
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/19377|yShodhganga
905__|afromsg

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