Title : Stereoselective total synthesis of biologically active lactones: Synargentolide A, Cryptofolione and Cryptocaryalactone along with the development of novel synthetic methodologies

Type of Material: Thesis
Title: Stereoselective total synthesis of biologically active lactones: Synargentolide A, Cryptofolione and Cryptocaryalactone along with the development of novel synthetic methodologies
Researcher: Balasubramanyam, P.
Guide: Das, Biswanath
Department: Department of Chemistry
Publisher: Jawaharlal Nehru Technological University, Hyderabad
Place: Hyderabad
Year: 2012
Language: English
Subject: Biologically
Lactones
Methodologies
Stereoselective
Synthesis
Dissertation/Thesis Note: PhD; Department of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2012
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_453890
040__|aJNTU_500028|dIN-AhILN
041__|aeng
100__|aBalasubramanyam, P.|eResearcher
110__|aDepartment of Chemistry|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017
245__|aStereoselective total synthesis of biologically active lactones: Synargentolide A, Cryptofolione and Cryptocaryalactone along with the development of novel synthetic methodologies
260__|aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2012
300__|c-|dNone|a226 p.
500__|aReferences p. 223-226
502__|bPhD|cDepartment of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2012
520__|aThe thesis entitled Stereoselective Total Synthesis of Biologically Active Lactones: Synargentolide A, Cryptofolione and newlineCryptocaryalactone along with the Development of Novel Synthetic Methodologies has been divided into three chapters. CHAPTER I: Stereoselective total synthesis of synargentolide A and its epimer newline Natural products containing and#945;, and#946;-unsaturated and#948;-lactone moiety exhibits various pharmacological properties such as cytotoxic, newlineantitumor, antibacterial, ant leukemic and antifungal activities. Synargentolide A 1, a compound of this group was isolated in 1998 by Collett and co-workers from Syncolostemon argentees. The basic structure of and#945;-pyrone 1 is a and#945;,and#946;-unsaturated and#948;-lactone connected to a newlinepolyoxygenated chain. Due to a large range of biological properties this moiety is very attractive to chemists to synthesize. newline
653__|aBiologically
653__|aLactones
653__|aMethodologies
653__|aStereoselective
653__|aSynthesis
700__|aDas, Biswanath|eGuide
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/19106|yShodhganga
905__|afromsg

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