Type of Material: | Thesis |
Title: | Stereoselective total synthesis of biologically active lactones: Synargentolide A, Cryptofolione and Cryptocaryalactone along with the development of novel synthetic methodologies |
Researcher: | Balasubramanyam, P. |
Guide: | Das, Biswanath |
Department: | Department of Chemistry |
Publisher: | Jawaharlal Nehru Technological University, Hyderabad |
Place: | Hyderabad |
Year: | 2012 |
Language: | English |
Subject: | Biologically | Lactones | Methodologies | Stereoselective | Synthesis |
Dissertation/Thesis Note: | PhD; Department of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2012 |
Fulltext: | Shodhganga |
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008 | __ | 240704t2012||||ii#||||g|m||||||||||eng|| |
035 | __ | |a(IN-AhILN)th_453890 |
040 | __ | |aJNTU_500028|dIN-AhILN |
041 | __ | |aeng |
100 | __ | |aBalasubramanyam, P.|eResearcher |
110 | __ | |aDepartment of Chemistry|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017 |
245 | __ | |aStereoselective total synthesis of biologically active lactones: Synargentolide A, Cryptofolione and Cryptocaryalactone along with the development of novel synthetic methodologies |
260 | __ | |aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2012 |
300 | __ | |c-|dNone|a226 p. |
500 | __ | |aReferences p. 223-226 |
502 | __ | |bPhD|cDepartment of Chemistry, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2012 |
520 | __ | |aThe thesis entitled Stereoselective Total Synthesis of Biologically Active Lactones: Synargentolide A, Cryptofolione and newlineCryptocaryalactone along with the Development of Novel Synthetic Methodologies has been divided into three chapters. CHAPTER I: Stereoselective total synthesis of synargentolide A and its epimer newline Natural products containing and#945;, and#946;-unsaturated and#948;-lactone moiety exhibits various pharmacological properties such as cytotoxic, newlineantitumor, antibacterial, ant leukemic and antifungal activities. Synargentolide A 1, a compound of this group was isolated in 1998 by Collett and co-workers from Syncolostemon argentees. The basic structure of and#945;-pyrone 1 is a and#945;,and#946;-unsaturated and#948;-lactone connected to a newlinepolyoxygenated chain. Due to a large range of biological properties this moiety is very attractive to chemists to synthesize. newline |
653 | __ | |aBiologically |
653 | __ | |aLactones |
653 | __ | |aMethodologies |
653 | __ | |aStereoselective |
653 | __ | |aSynthesis |
700 | __ | |aDas, Biswanath|eGuide |
856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/19106|yShodhganga |
905 | __ | |afromsg |
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