Title : Immunomodulatory Effect of Recombinant Interleukin 2 in Chickens Vaccinated Against New Castle Disease (Applied for Patent)

Type of Material: Thesis
Title: Immunomodulatory Effect of Recombinant Interleukin 2 in Chickens Vaccinated Against New Castle Disease (Applied for Patent)
Researcher: Shambulingappa, B. E.
Guide: Padalkar, R. D.
Department: Faculty of Biotechnology
Publisher: Jawaharlal Nehru Technological University, Hyderabad
Place: Hyderabad
Year: 2012
Language: English
Subject: Disease
Immunomodulatory
Interleukin
Recombinant
Vaccinated
Biotechnology
Medical and Health Sciences
Dissertation/Thesis Note: PhD; Faculty of Biotechnology, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2012
Fulltext: Shodhganga

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035__|a(IN-AhILN)th_453838
040__|aJNTU_500028|dIN-AhILN
041__|aeng
100__|aShambulingappa, B. E.|eResearcher
110__|aFaculty of Biotechnology|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017
245__|aImmunomodulatory Effect of Recombinant Interleukin 2 in Chickens Vaccinated Against New Castle Disease (Applied for Patent)
260__|aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2012
300__|c-|dNone|a164 p.
500__|aReferences p.113-164 ((Applied for Patent))
502__|bPhD|cFaculty of Biotechnology, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2012
520__|aRecombinant Interleukin-2 is gaining marked importance due to its potential application in immunomodulation of vaccinated livestock animals and thereby reducing mortality newlinerates during outbreak of infectious diseases. Various serological tests were conducted to assess the specific immune response newline(both humeral and cell mediated immune response) by knowing the antibody titers of serum samples collected from vaccinated newlinepoultry birds along with IL-2 therapy. newline ELISA titres (OD values) were significantly higher in group-A newlinechickens up to 1.453±0.007 which received both vaccination and Recombinant IL-2.In group-B (Vaccinated control) showed the OD newlinevalues up to 0.813±0.003 and least values were recorded in group-C (unvaccinated control).This clearly indicated enhanced humoral response in the birds receiving both vaccination and RecIL-2 inoculation. The results in the present study were highly newlineremarkable and significant that HI titres were increased up to 1:512 (
650__|aBiotechnology|2UGC
650__|aMedical and Health Sciences|2AIU
653__|aDisease
653__|aImmunomodulatory
653__|aInterleukin
653__|aRecombinant
653__|aVaccinated
700__|eGuide|aPadalkar, R. D.
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/18989|yShodhganga
905__|afromsg

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