| Type of Material: | Thesis |
| Title: | Design and development of oral modified release dosage forms of highly soluble drugs |
| Researcher: | Rao, Maram Sambasiva |
| Guide: | Vidyadhara, S. | Raju, N. V. S. |
| Department: | Faculty of Pharmaceutical Sciences |
| Publisher: | Jawaharlal Nehru Technological University, Hyderabad |
| Place: | Hyderabad |
| Year: | 2013 |
| Language: | English |
| Subject: | Design | Development | Dosage | Drugs | Modified | Medical Sciences | Medical and Health Sciences |
| Dissertation/Thesis Note: | PhD; Faculty of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2013 |
| Fulltext: | Shodhganga |
| 000 | 00000ntm a2200000ua 4500 | |
| 001 | 453825 | |
| 003 | IN-AhILN | |
| 005 | 2024-06-27 17:21:21 | |
| 008 | __ | 240627t2013||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_453825 |
| 040 | __ | |aJNTU_500028|dIN-AhILN |
| 041 | __ | |aeng |
| 100 | __ | |aRao, Maram Sambasiva|eResearcher |
| 110 | __ | |aFaculty of Pharmaceutical Sciences|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017 |
| 245 | __ | |aDesign and development of oral modified release dosage forms of highly soluble drugs |
| 260 | __ | |aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2013 |
| 300 | __ | |a206 p.|c- |
| 500 | __ | |aBiblography p. 194-206 |
| 502 | __ | |cFaculty of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2013|bPhD |
| 520 | __ | |aThe ultimate goal of the study was to develop a stable, cost effective modified release dosage form of highly soluble drugs such as newlineTrimetazidine dihydrochloride, Glucosamine hydrochloride and Tramadol hydrochloride. It was further aimed to perform the bioavailability and bioequivalence studies for selected model drugs i.e. Trimetazidine dihydrochloride and Glucosamine hydrochloride. Initially the drug-polymer interactions were studied for three model newlinedrugs with excipients by physical bservation, chemical analysis and FTIR studies. The results found that three model drugs were newlinecompatible with excipients present in the study. Trimetazidine dihydrochloride modified release tablets were newlineprepared by direct compression technique by using Xanthan gum and newlinePolyethylene oxide as release modifiers in different concentrations. newlineGlucosamine hydrochloride tablets were prepared by wet newlinegranulation technique by using HPMC K100M and HPMC K200M as a newlinerate controlling po |
| 650 | __ | |aMedical Sciences|2UGC |
| 650 | __ | |aMedical and Health Sciences|2AIU |
| 653 | __ | |aDesign |
| 653 | __ | |aDevelopment |
| 653 | __ | |aDosage |
| 653 | __ | |aDrugs |
| 653 | __ | |aModified |
| 700 | __ | |aVidyadhara, S.|eGuide |
| 700 | __ | |eGuide|aRaju, N. V. S. |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/18958|yShodhganga |
| 905 | __ | |afromsg |
User Feedback Comes Under This section.