| Type of Material: | Thesis |
| Title: | Synthesis of Mercapto-(Oxadiazole/Triazole) Carboxylic acid Compounds and their derivatives of Biological interest |
| Researcher: | Rao, Manikrao Anil Madhav |
| Guide: | Chaple |
| Department: | Faculty of Pharmaceutical Sciences |
| Publisher: | Jawaharlal Nehru Technological University, Hyderabad |
| Place: | Hyderabad |
| Year: | 2012 |
| Language: | English |
| Subject: | Biological | Carboxylic | Mercapto | Oxadiazole | Triazole |
| Dissertation/Thesis Note: | PhD; Faculty of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad; 2012 |
| Fulltext: | Shodhganga |
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| 001 | 453727 | |
| 003 | IN-AhILN | |
| 005 | 2024-06-12 18:06:55 | |
| 008 | __ | 240612t2012||||ii#||||g|m||||||||||eng|| |
| 035 | __ | |a(IN-AhILN)th_453727 |
| 040 | __ | |aJNTU_500028|dIN-AhILN |
| 041 | __ | |aeng |
| 100 | __ | |aRao, Manikrao Anil Madhav|eResearcher |
| 110 | __ | |aFaculty of Pharmaceutical Sciences|bJawaharlal Nehru Technological University, Hyderabad|dHyderabad|ein|0U-0017 |
| 245 | __ | |aSynthesis of Mercapto-(Oxadiazole/Triazole) Carboxylic acid Compounds and their derivatives of Biological interest |
| 260 | __ | |aHyderabad|bJawaharlal Nehru Technological University, Hyderabad|c2012 |
| 300 | __ | |c-|dNone|aP. 249 |
| 500 | __ | |aReferences p. 242-243 |
| 502 | __ | |bPhD|cFaculty of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Hyderabad, Hyderabad|d2012 |
| 520 | __ | |aThe research work reported in this dissertation consists of synthesis ofnewlinepharmacologically active compounds and the modification of their structure according to the result of pharmacological screening. All these synthesized compounds were characterized by satisfactory spectroscopic data. These compounds belongs to the classes of 1,3,4-oxadiazole-2(3H)-thione and 1,2,4-newlinetriazole-3(4H)-thione. All these compounds were screened for different biologicalnewlineactivities including bactericidal, fungicidal, analgesic, anti-inflammatory,newlineanxiolytic and anticonvulsant activities and as expected most of them had exhibited moderate to good activities. Scheme I and Scheme II: Here focus was made mainly on the synthesis of 1,2,4- triazoline-3-thione as the essential pharmacophore and investigation of its combination with various N-substituted carboxamidoalkylthio moiety through sulfur atom and converting them to corresponding sulfoxides and sulfones selectively by solid state green oxidation method u |
| 653 | __ | |aBiological |
| 653 | __ | |aCarboxylic |
| 653 | __ | |aMercapto |
| 653 | __ | |aOxadiazole |
| 653 | __ | |aTriazole |
| 700 | __ | |aChaple|eGuide |
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/18477|yShodhganga |
| 905 | __ | |afromsg |
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