Title : Studies in the Borane-mediated asymmetric reduction of prochiral ketones catalyzed by chiral phosphoramides, diamines and amides

Type of Material: Thesis
Title: Studies in the Borane-mediated asymmetric reduction of prochiral ketones catalyzed by chiral phosphoramides, diamines and amides
Researcher: Das, Utpal
Guide: Basavaiah, D.
Department: School of Chemistry
Publisher: University of Hyderabad, Hyderabad
Place: Hyderabad
Year: June, 2009
Language: English
Subject: Chemistry
Dissertation/Thesis Note: PhD
Fulltext: Shodhganga
University of Hyderabad

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035__|a(IN-AhILN)th_447307
040__|aHYDR_500046|dIN-AhILN
041__|aeng
100__|aDas, Utpal|eResearcher
110__|aSchool of Chemistry|bUniversity of Hyderabad, Hyderabad|dHyderabad|ein
245__|aStudies in the Borane-mediated asymmetric reduction of prochiral ketones catalyzed by chiral phosphoramides, diamines and amides
260__|cJune, 2009|aHyderabad|bUniversity of Hyderabad, Hyderabad
300__|axii, 226p.|dNone
500__|aAppendix 226p.
502__|bPhD
518__|oDate of Award|d2009
518__|oDate of Registration|dn.d.
520__|aEnantiomerically pure (or enriched) secondary alcohols occupy an important place in chiral chemistry because several chiral secondary alcohols are medicinally useful compounds. Due to the remarkable applications of chiral secondary alcohols as medicinally relevant molecules and also as synthon for obtaining various biologically active compounds there has been an increasing interest in developing simple and practical methodologies for synthesis of different chiral secondary alcohols. Among various available and known methods, asymmetric reduction of prochiral ketones has become one of the most important methods for obtaining enantiopure (or enriched) secondary alcohols. This thesis deals with the synthesis and application of chiral catalytic sources containing N-P=O structural framework, diamines and amides for the borane-mediated asymmetric reduction of prochiral ketones and it contains three chapters: 1) Introduction, 2) Objectives, Results and Discussion and 3) Experimental. The first chapter presents bri
653__|aChemistry
700__|aBasavaiah, D.|eGuide
856__|uhttp://shodhganga.inflibnet.ac.in/handle/10603/4246|yShodhganga
856__|uhttp://igmlnet.uohyd.ac.in:8000/hi-res/hcu_images/TH5467.pdf|yUniversity of Hyderabad
905__|afromsg

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