| Type of Material: | Thesis | 
| Title: | X-ray crystallographic studies on HIV-1 protease | 
| Researcher: | Das, Amit | 
| Guide: | Hosur, M V | 
| Department: | Department of Chemical Sciences | 
| Publisher: | Homi Bhabha National Institute | 
| Place: | Mumbai | 
| Year: | 09-03-2012 | 
| Language: | English | 
| Subject: | Crystal structure | Hiv-1 protease | Enzyme | Catalysis | Mechanism | Drug resistance | Substrate | Rt-rh | Tfr-pr | Tetrahedral intermediate | 
| Dissertation/Thesis Note: | PhD | 
| Fulltext: | Shodhganga | 
| 000 | 00000ntm a2200000ua 4500 | |
| 001 | 263151 | |
| 003 | IN-AhILN | |
| 005 | 2013-12-05 09:06:19 | |
| 008 | __ | 120913t2012||||ii#||||g|m||||||||||eng|| | 
| 035 | __ | |a(IN-AhILN)th_263151 | 
| 040 | __ | |aHBNI_400088|dIN-AhILN | 
| 041 | __ | |aeng | 
| 100 | __ | |aDas, Amit|eResearcher | 
| 110 | __ | |aDepartment of Chemical Sciences|bHomi Bhabha National Institute|dMumbai | 
| 245 | __ | |aX-ray crystallographic studies on HIV-1 protease | 
| 260 | __ | |aMumbai|bHomi Bhabha National Institute|c09-03-2012 | 
| 502 | __ | |bPhD | 
| 518 | __ | |oDate of Notification|d2012-03-09 | 
| 520 | __ | |aThe unique contribution of the candidate is structural mapping of the peptide bond cleavage reaction catalyzed by HIV-1 protease (HIV-1 PR). The candidate has obtained the first crystal structures of complexes between an active HIV-1 PR enzyme and natur | 
| 653 | __ | |aCrystal structure | 
| 653 | __ | |aHiv-1 protease | 
| 653 | __ | |aEnzyme | 
| 653 | __ | |aCatalysis | 
| 653 | __ | |aMechanism | 
| 653 | __ | |aDrug resistance | 
| 653 | __ | |aSubstrate | 
| 653 | __ | |aRt-rh | 
| 653 | __ | |aTfr-pr | 
| 653 | __ | |aTetrahedral intermediate | 
| 700 | __ | |aHosur, M V|eGuide | 
| 856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/4694|yShodhganga | 
| 905 | __ | |anotification | 
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