Type of Material: | Thesis |
Title: | Total syntheses of indole alkaloids - (±)-Physovenine, (±)- Physostigmine, (±)-Coerulescine and (±)-Horsfiline |
Researcher: | Dhondge, Attrimuni Parshuram |
Guide: | Kulkarni, M G |
Department: | Department of Chemistry |
Publisher: | Savitribai Phule Pune University |
Place: | Pune |
Year: | 2010 |
Language: | English |
Subject: | Chemistry | Chemical Science | Indole Alkaloids | Chemistry |
Dissertation/Thesis Note: | PhD |
Fulltext: | Shodhganga |
000 | 00000ctm a2200000ua 4500 | |
001 | 254561 | |
003 | IN-AhILN | |
005 | 2023-07-07 13:59:00 | |
008 | __ | 120419t2010||||ii#||||g|m||||||||||eng|| |
035 | __ | |a(IN-AhILN)th_254561 |
040 | __ | |aPUNE_411007|dIN-AhILN |
041 | __ | |aeng |
100 | __ | |aDhondge, Attrimuni Parshuram|eResearcher |
110 | __ | |aDepartment of Chemistry|bSavitribai Phule Pune University|dPune|ein |
245 | __ | |aTotal syntheses of indole alkaloids - (±)-Physovenine, (±)- Physostigmine, (±)-Coerulescine and (±)-Horsfiline |
260 | __ | |bSavitribai Phule Pune University|c2010|aPune |
300 | __ | |a266p. |
502 | __ | |bPhD |
518 | __ | |oDate of Notification|d2010-04-01 |
520 | __ | |aTotal synthesis of natural products has evolved as major programme in the organic laboratories world over. The synthesis of these compounds needs, apart from meticulous planning and ingenious strategies for assembling these structures with due attention paid to the chemo-, region-, and stereoselectivities, developing novel methodologies for constructing the complex structures of the natural products. The Wittig Olefination-Claisen rearrangement protocol developed in our laboratory was applied, in the present context, to the syntheses 4-pentenals from appropriate o-Nitro aryl derivative. Such 4-pentenals were used as an intermediate for developing novel syntheses of biologically significant alkaloids like (±)-Physovenine, (±)-Physostigmine, (±)- Coerulescine and (±)-Horsfiline. Accordingly, the thesis is divided into the three chapters. Chapter 1: Total synthesis of (±)-Physovenine. This chapter describes the total synthesis of (±)-Physovenine using Wittig Olefination – Claisen rearrangement protocol |
653 | __ | |aChemistry |
653 | __ | |aChemical Science |
653 | __ | |aIndole Alkaloids |
653 | __ | |aChemistry |
700 | __ | |aKulkarni, M G|eGuide |
856 | __ | |uhttp://shodhganga.inflibnet.ac.in/handle/10603/3419|yShodhganga |
905 | __ | |anotification |
User Feedback Comes Under This section.